574-95-8 Usage
Description
Aureothricin is an antibiotic that was first described by Umezawa and co-workers in Japan in 1949. It is a more hydrophobic analogue of thiolutin and has gained significant attention due to its selective antitumor activity. Aureothricin is known for its potent inhibition of bacterial and yeast RNA polymerases, its ability to inhibit mannan and glucan formation in fungi, and its role in inhibiting tumor-cell induced angiogenesis in vivo.
Uses
Used in Anticancer Applications:
Aureothricin is used as an anticancer agent for its selective antitumor activity. It is particularly effective against various types of cancer due to its ability to inhibit RNA polymerases in bacteria and yeast, as well as its role in preventing tumor-cell induced angiogenesis in vivo.
Used in Pharmaceutical Industry:
Aureothricin is used as an antibiotic in the pharmaceutical industry for its potent inhibition of bacterial and yeast RNA polymerases. This property makes it a valuable compound in the development of new drugs to combat bacterial and yeast infections.
Used in Fungal Infections Treatment:
Aureothricin is used as an antifungal agent for its ability to inhibit mannan and glucan formation in fungi. This application is particularly useful in treating various fungal infections and developing new antifungal drugs.
Used in Drug Delivery Systems:
Aureothricin's hydrophobic nature and its various biological activities make it a promising candidate for use in drug delivery systems. These systems can be designed to improve the delivery, bioavailability, and therapeutic outcomes of aureothricin, enhancing its potential in treating various medical conditions, including cancer and fungal infections.
Check Digit Verification of cas no
The CAS Registry Mumber 574-95-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,7 and 4 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 574-95:
(5*5)+(4*7)+(3*4)+(2*9)+(1*5)=88
88 % 10 = 8
So 574-95-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H10N2O2S2/c1-3-6(12)10-7-8-5(4-14-15-8)11(2)9(7)13/h4H,3H2,1-2H3,(H,10,12)