574007-66-2 Usage
Description
1-Piperazinecarboxylic acid, 2,6-diMethyl-, 1,1-diMethylethyl ester, (2S,6S)is an organic compound with the molecular formula C10H20N2O2. It is a derivative of piperazine carboxylic acid, featuring two methyl groups at the 2nd and 6th positions and an ester group attached to the 1st position. 1-Piperazinecarboxylic acid, 2,6-diMethyl-, 1,1-diMethylethyl ester, (2S,6S)is characterized by its potential applications in the pharmaceutical industry, particularly in the development of selective inhibitors.
Uses
Used in Pharmaceutical Industry:
1-Piperazinecarboxylic acid, 2,6-diMethyl-, 1,1-diMethylethyl ester, (2S,6S)is used as a key intermediate compound for the synthesis of Jak1 selective inhibitors. These inhibitors play a crucial role in the development of targeted therapies for various diseases, including autoimmune disorders and certain types of cancer. 1-Piperazinecarboxylic acid, 2,6-diMethyl-, 1,1-diMethylethyl ester, (2S,6S)-'s unique structure allows for the design of highly specific and potent Jak1 inhibitors, which can help in modulating the immune response and treating related conditions more effectively.
Check Digit Verification of cas no
The CAS Registry Mumber 574007-66-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,7,4,0,0 and 7 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 574007-66:
(8*5)+(7*7)+(6*4)+(5*0)+(4*0)+(3*7)+(2*6)+(1*6)=152
152 % 10 = 2
So 574007-66-2 is a valid CAS Registry Number.
InChI:InChI=1/C11H22N2O2/c1-8-6-12-7-9(2)13(8)10(14)15-11(3,4)5/h8-9,12H,6-7H2,1-5H3/t8-,9-/m0/s1
574007-66-2Relevant articles and documents
JAK1 SELECTIVE INHIBITORS
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Page/Page column 52; 53; 54; 58, (2018/08/12)
Disclosed herein are compounds of Formula (I), and pharmaceutically acceptable salts thereof, wherein R1-R8 have any of the meanings defined herein. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I) and methods of using the same.
FUSED TRICYCLIC AMIDE COMPOUNDS AS MULTIPLE KINASE INHIBITORS
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, (2015/01/16)
Provided are fused tricyclic amide compounds, pharmaceutical compositions comprising at least one such fused tricyclic compound, processes for the preparation thereof, and the use thereof in therapy. Disclosed herein are certain tricyclic amide compounds that can be useful for inhibiting multiple (specifically BRAF and/or EGFR-T790M) kinases and for treating disorders mediated thereby.
DIHYDROPYRIDOPHTHALAZINONE INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP)
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Page/Page column 93, (2010/03/02)
A compound having the structure set forth in Formula (I) and Formula (II): wherein the substituents Y, Z, A, B, R1, R2, R3, R4 and R5 are as defined herein. Provided herein are inhibitors of poly(ADP-ribose)polymerase activity. Also described herein are pharmaceutical compositions that include at least one compound described herein and the use of a compound or pharmaceutical composition described herein to treat diseases, disorders and conditions that are ameliorated by the inhibition of PARP activity.
