57404-85-0Relevant articles and documents
RAS INHIBITORS AND METHODS OF USING THE SAME
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Paragraph 000150, (2021/08/06)
Provided herein are compounds identified as inhibitors of KRAS protein activity that can be used to treat various diseases and disorders, such as cancer.
KRAS G12D INHIBITORS
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Paragraph 0812, (2021/03/05)
The present invention relates to compounds that inhibit KRas G12D. In particular, the present invention relates to compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor.
Synthesis and Photochromism of Novel Pyridyl-Substituted Naphthopyrans
De Azevedo, Orlando D. C. C.,Elliott, Paul I. P.,Gabbutt, Christopher D.,Heron, B. Mark,Lord, Kyle J.,Pullen, Christopher
, p. 10772 - 10796 (2020/09/23)
Multitarget synthetic strategies to access novel photochromic 3H-naphtho[2,1-b]pyrans decorated with pyridyl units are described. The new pyridyl-substituted 3H-naphtho[2,1-b]pyrans display good photochromic properties with reversible generation of photomerocyanines, which exhibit mainly orange/red hues. Photochromic parameters including photocolorability and persistence of color vary tremendously on structural modification of the naphthopyran core.