5743-22-6

Basic information

• Product Name: caffeine salicylate
• Synonyms: caffeine salicylate
• CAS NO: 5743-22-6
• Molecular Formula: C₇H₆O₃*C₈H₁₀N₄O₂
• Molecular Weight: 332.31134
• EINECS: 227-259-4
• Mol File: 5743-22-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 416.8°Cat760mmHg
• Flash Point: 205.9°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 3.72E-07mmHg at 25°C
• CAS DataBase Reference: caffeine salicylate(CAS DataBase Reference)
• NIST Chemistry Reference: caffeine salicylate(5743-22-6)
• EPA Substance Registry System: caffeine salicylate(5743-22-6)

Safety Data

• Hazardous Substances Data: 5743-22-6(Hazardous Substances Data)

Usage

General Description

Caffeine salicylate is a compound formed from the combination of caffeine and salicylic acid. It is used as a central nervous system stimulant and a nonsteroidal anti-inflammatory drug (NSAID). Caffeine salicylate is known for its analgesic and anti-inflammatory properties, making it useful for the treatment of mild to moderate pain, including headaches, muscle aches, and toothaches. It is also found in several over-the-counter medications, such as headache and menstrual relief formulas. However, due to its potential for serious side effects and interactions with other drugs, caffeine salicylate should be used with caution and under the guidance of a healthcare professional.

InChI:InChI=1/C8H10N4O2.C7H6O3/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2;8-6-4-2-1-3-5(6)7(9)10/h4H,1-3H3;1-4,8H,(H,9,10)

Upstream product

• 58-08-2 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione 
• 69-72-7 salicylic acid 

Relevant articles and documents

Assessment of Co-sublimation for the Formation of Multicomponent Crystals

The merits of co-sublimation and mechanochemistry as screening techniques for multicomponent crystal formation are compared. Several multicomponent crystals that can be formed both mechanochemically and by sublimation are investigated, allowing for a comparison between the relatively unknown technique of co-sublimation and a well-known, robust solid-state screening methodology. This work aims to determine the general utility and versatility of co-sublimation in the preparation of multicomponent crystals. Co-crystals and salts, as well as their polymorphs, have been investigated, and problems that can arise due to sublimation temperature differences, isomerization, and degradation are discussed. Co-sublimation is shown to be a valuable co-crystallization technique for the discovery and identification of new multicomponent materials.

Microfluidic approach to cocrystal screening of pharmaceutical parent compounds

We describe a microfluidic approach to screen for the formation of cocrystalline solid forms of pharmaceutical parent compounds (PCs). Saturated solutions of PCs and of cocrystal formers dissolved in a variety of solvents are precisely metered in arrays o