57467-16-0

Basic information

• Product Name: 4-nitrophenyl 2-(acetylamino)-2-deoxy-6-O-beta-D-galactopyranosyl-beta-D-glucopyranoside
• Synonyms: beta-D-Glucopyranoside, 4-nitrophenyl 2-(acetylamino)-2-deoxy-6-O-beta-D-galactopyranosyl-
• CAS NO: 57467-16-0
• Molecular Formula: C₂₀H₂₈N₂O₁₃
• Molecular Weight: 504.4419
• Mol File: 57467-16-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 882.9°C at 760 mmHg
• Flash Point: 487.8°C
• Density: 1.61g/cm³
• Vapor Pressure: 2.12E-33mmHg at 25°C
• Refractive Index: 1.647
• CAS DataBase Reference: 4-nitrophenyl 2-(acetylamino)-2-deoxy-6-O-beta-D-galactopyranosyl-beta-D-glucopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: 4-nitrophenyl 2-(acetylamino)-2-deoxy-6-O-beta-D-galactopyranosyl-beta-D-glucopyranoside(57467-16-0)
• EPA Substance Registry System: 4-nitrophenyl 2-(acetylamino)-2-deoxy-6-O-beta-D-galactopyranosyl-beta-D-glucopyranoside(57467-16-0)

Safety Data

• Hazardous Substances Data: 57467-16-0(Hazardous Substances Data)

Upstream product

• 3459-18-5 4-nitrophenyl N-acetyl-β-D-glucosaminide 
• 2816-24-2 o-nitrophenyl D-galactopyranoside 
• 3150-24-1 4-nitrophenyl-β-D-galactopyranoside 

Relevant articles and documents

Enhanced enzymatic reactions in a microchannel reactor

Organic and enzymatic reactions in microchannel reactors were discussed. Hydrolytic activity of a microchannel pre-treated with enzyme solution was studied. It was found that the reaction rate in microchannel is much faster than the micro test tube. Mass transfer is also much more efficient in microchannel.

A convenient synthesis of β-D-galactosyl disaccharide derivatives using the β-D-galactosidase from Bacillus circulans

β-D-Gal-(1 → 4)-β-D-GlcNAc-OC6H4NO2-p (p-nitrophenyl N-acetyl-β-lactosaminide) and β-D-Gal-(1 → 6)-β-D-GlcNAc-OC6H4NO2-p (p-nitrophenyl N-acetyl-β-isolactosaminide) were regioselectively synthesized from lactose and p-nitrophenyl 2-acetamido-2-deoxy-glucopyranoside, employing transglycosylation by the β-D-galactosidase from Bacillus circulans and by controlling the concentration of organic solvent in the reaction system. The (1 → 4)-linked disaccharide was formed exclusively when the concentration of organic solvent was high, whereas the (1 → 6)-linked isomer was produced with a low concentration. Further utilization of the transglycosylation by the enzyme led to the regioselective formation of β-D-Gal-(1 → 4)-D-GalNAc and β-D-Gal-(1 → 4)-β-D-GalNAc-OC6H4NO2-p. With the enzyme, β-D-galactosyl transfer occurred preferentially at the O-4 position of GlcNAc and GalNAc, regardless of the configuration of the hydroxyl group. β-D-Gal-(1→4)-b-D-GlcNAc-OC6H4NO2-p (p-nitrophenyl N-acetyl-β-lactosaminide) and β-D-Gal-(1→6)-β-D-GlcNAc-OC6H4NO2-p (p-nitrophenyl N-acetyl-β-isolactosaminde) were regioselectively synthesized from lactose and p-nitrophenyl 2-acetamido-2-deoxy-glucopyranoside, employing transglycosylation by the b-D-galactosidas from Bacillus circulans and by controlling the concentration of organic solvent in the reaction system. The (1→4) linked disaccharide was formed exclusively when the concentration of organic solvent was high, whereas the (1→6)-linked isomer was produced with a low concentration. Further utilization of the transglycosylation by the enzyme led to the regioselective formation of β-D-Gal-(1→4)-D-GalNAc and β-D-Gal-(1→4)-β-D-GalNAc-OC6H4NO2-p. With the enzyme, β-D-galactosyl transfer occurred preferentially at the O-4 position of GlcNAc, regardless of the configuration of the hydroxyl group.