574704-99-7

Basic information

• Product Name: 4-[1-(1-tert-butoxycarbonyl-ethylcarbamoyl)-3-methyl-butylcarbamoyl]-4-phenyl-piperidine-1-carboxylic acid tert-butyl ester
• CAS NO: 574704-99-7
• Molecular Weight: 545.72
• Mol File: 574704-99-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[1-(1-tert-butoxycarbonyl-ethylcarbamoyl)-3-methyl-butylcarbamoyl]-4-phenyl-piperidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[1-(1-tert-butoxycarbonyl-ethylcarbamoyl)-3-methyl-butylcarbamoyl]-4-phenyl-piperidine-1-carboxylic acid tert-butyl ester(574704-99-7)
• EPA Substance Registry System: 4-[1-(1-tert-butoxycarbonyl-ethylcarbamoyl)-3-methyl-butylcarbamoyl]-4-phenyl-piperidine-1-carboxylic acid tert-butyl ester(574704-99-7)

Safety Data

• Hazardous Substances Data: 574704-99-7(Hazardous Substances Data)

Upstream product

• 52961-24-7 H-L-Leu-L-Ala-OtBu 
• 167262-68-2 N-(t-butyloxycarbonyl)-4-phenylpiperidine-4-carboxylic acid 

Downstream Products

• 256368-78-2 2-(2-{[1-(2-tert-butoxycarbonylamino-3-tritylsulfanyl-propionyl)-4-phenyl-piperidine-4-carbonyl]-amino}-4-methyl-pentanoylamino)-propionic acid tert-butyl ester 

Relevant articles and documents

Antifungal activity of a Candida albicans GGTase I inhibitor-alanine conjugate. Inhibition of Rho1p prenylation in C. albicans

An alanine conjugate of a Candida albicans geranylgeranyl transferase I inhibitor was synthesized to facilitate its uptake into the fungal cell. The antifungal activity of CaGGTase-Ala conjugate is demonstrated. It is also shown that the CaGGTase-Ala conjugate affects prenylation of endogenous Rho1p, but has no effect on prenylation of endogenous Ras1p.