57479-65-9

Basic information

• Product Name: Methanone, (2-aminophenyl)(3-chlorophenyl)-
• CAS NO: 57479-65-9
• Molecular Formula: C13H10ClNO
• Molecular Weight: 231.681
• Mol File: 57479-65-9.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Methanone, (2-aminophenyl)(3-chlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (2-aminophenyl)(3-chlorophenyl)-(57479-65-9)
• EPA Substance Registry System: Methanone, (2-aminophenyl)(3-chlorophenyl)-(57479-65-9)

Safety Data

• Hazardous Substances Data: 57479-65-9(Hazardous Substances Data)

Upstream product

• 108-37-2 1-bromo-3-chlorobenzene 
• 133776-41-7 anthranilic acid N-methoxy-N-methylamide 
• 96245-64-6 2-[(3-Chloro-phenyl)-imino-methyl]-phenylamine 
• 2999-00-0 3-chloro-benzophenone-seqcis-oxime 
• 1885-29-6 anthranilic acid nitrile 
• 118-48-9 isatoic anhydride 
• 766-84-7 3-chloro-benzonitrile 
• 62-53-3 aniline 
• 118-92-3 anthranilic acid 
• 103-84-4 Acetanilid 
• 1335211-11-4 N-(2-(3-chlorobenzoyl)phenyl)acetamide 
• 36229-42-2 (3-chlorophenyl)magnesium bromide 
• 3136-53-6 3-chloro-benzophenone-seqtrans-oxime 

Downstream Products

• 96245-65-7 2-amino>-3'-chlorobenzophenone 
• 73147-08-7 4-(3-chlorophenyl)quinazoline 
• 890098-14-3 C₁₃H₈ClIO 
• 28059-64-5 2-benzylaniline 
• 95276-09-8 9-(3-chlorophenyl)acridine 
• 1597443-31-6 (2-aminophenyl)(3-chlorophenyl)methanone oxime 
• 1449372-82-0 3-acetyl-4-(3-chlorophenyl)quinolin-2(1H)-one 
• 1449373-18-5 (E)-4-(3-chlorophenyl)-3-[3-(4-chlorophenyl)acryloyl]quinolin-2(1H)-one 
• 1449374-07-5 4-{5-(4-chlorophenyl)-3-[4-(3-chlorophenyl)-2-oxo-1,2-dihydroquinolin-3-yl]-4,5-dihydro-1H-pyrazol-1-yl}-4-oxobutanoic acid 
• 1449373-63-0 4-(3-chlorophenyl)-3-[5-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-3-yl]quinolin-2(1H)-one 

Relevant articles and documents

Asymmetric Synthesis of Hydroquinazolines Bearing C4-Tetrasubstituted Stereocenters via Kinetic Resolution of α-Tertiary Amines

A novel protocol for asymmetric synthesis of hydroquinazolines bearing C4-tetrasubstituted stereocenters has been achieved through kinetic resolution of 2-amido α-tertiary benzylamines via chiral phosphoric acid catalyzed intramolecular dehydrative cyclizations. This method gave access to both α-tertiary benzylamines and hydroquinazolines with broad scope and high enantioselectivities. An intriguing restricted rotation of the C-N bond was observed for hydroquinazoline products bearing C4-tetrasubstituted stereocenters.

One-Pot Synthesis of Spirocyclopenta[ a]indene Derivatives via a Cascade Ring Expansion and Intramolecular Friedel-Crafts-Type Cyclization

A one-pot efficient synthetic approach for the rapid construction of spirocyclopenta[a]indene derivatives has been developed via an iodine-initiated cascade ring expansion and intramolecular Friedel-Crafts-type cyclization from propargyl alcohol-tethered alkylidenecyclobutanes under mild conditions with broad substrate scope. This cascade process can be elegantly conducted on a gram scale. A plausible reaction mechanism has been proposed on the basis of a series of deuterium labeling and control experiments.

A one-pot process for palladium catalyzed direct C-H acylation of anilines in water using a removable ortho directing group

A new mild, practical method for the synthesis of aminobenzophenone derivatives through a three step one-pot reaction sequence involving acylation of anilines, palladium catalyzed cross-dehydrogenative coupling of the formed anilides and the hydrolytic cleavage is reported. The full reaction sequence was performed under aqueous conditions.