5751-84-8Relevant articles and documents
Raltitrexed pharmaceutical composition and preparation method thereof
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, (2018/04/02)
The invention relates to a raltitrexed pharmaceutical composition which is high in safety and a preparation method thereof. The raltitrexed pharmaceutical composition comprises raltitrexed and thiophene related substances, wherein the content of the thiophene related substances is not higher than 0.3%. The raltitrexed pharmaceutical composition is good in safety, effectiveness and stability and can relieve the blood toxicity of the raltitrexed to a certain degree.
Improved modular synthesis of thieno[3,2-b]pyrroles and thieno[2,3-b]pyrroles
Malancona, Savina,Hernando, Josè I. Martin,Attenni, Barbara,Ontoria, Jesus M.,Narjes, Frank
supporting information; experimental part, p. 1625 - 1628 (2009/06/18)
A convenient modular synthesis for the construction of densely functionalized thieno[3,2-b]pyrroles, allosteric inhibitors of the Hepatitis C virus NS5B polymerase, is described. The route allows the introduction of substituents in positions 4, 5, and 6 o
THIENOPYRROLES AS ANTIVIRAL AGENTS
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Page/Page column 50, (2008/06/13)
The present invention relates to thienopyrrole compounds of formula (I); wherein A, B, Y, Ar, n, Z and X1 are as defined herein, and pharmaceutically acceptable salts thereof, useful in the prevention and treatment of hepatitis C infections.