57531-88-1

Basic information

• Product Name: 2,5,6-Trichloro-4-propoxy-1,3-benzenedicarbonitrile
• Synonyms: 2,5,6-Trichloro-4-propoxy-1,3-benzenedicarbonitrile
• CAS NO: 57531-88-1
• Molecular Formula: C₁₁H₇Cl₃N₂O
• Molecular Weight: 289.5451
• Mol File: 57531-88-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 406.4°Cat760mmHg
• Flash Point: 199.6°C
• Appearance: /
• Density: 1.45g/cm³
• Vapor Pressure: 8.17E-07mmHg at 25°C
• Refractive Index: 1.579
• CAS DataBase Reference: 2,5,6-Trichloro-4-propoxy-1,3-benzenedicarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5,6-Trichloro-4-propoxy-1,3-benzenedicarbonitrile(57531-88-1)
• EPA Substance Registry System: 2,5,6-Trichloro-4-propoxy-1,3-benzenedicarbonitrile(57531-88-1)

Safety Data

• Hazardous Substances Data: 57531-88-1(Hazardous Substances Data)

Usage

General Description

2,5,6-Trichloro-4-propoxy-1,3-benzenedicarbonitrile is a chemical compound with the molecular formula C10H5Cl3N2O. It is a colorless solid that is commonly used as an herbicide, particularly in controlling grasses and broadleaf weeds in various crops. It works by inhibiting the enzyme photosystem II, which ultimately disrupts the process of photosynthesis in plants, leading to their death. 2,5,6-Trichloro-4-propoxy-1,3-benzenedicarbonitrile is known for its selective action against certain plant species and its low toxicity to mammals, making it a widely used herbicide in agriculture. However, it is important to handle and use this compound with caution as it can be harmful if ingested or inhaled, and can also cause skin and eye irritation.

InChI:InChI=1/C11H7Cl3N2O/c1-2-3-17-11-7(5-16)8(12)6(4-15)9(13)10(11)14/h2-3H2,1H3

Upstream product

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Relevant articles and documents

Synthesis and antiinflammatory evaluation of substituted isophthalonitriles, trimesonitriles, benzonitriles, and terephthalonitriles

In an effort to develop nonacidic, nonsteroidal, antiinflammatory agents without gastrointestinal complications, a series of cyanobenzenes was synthesized for antiinflammatory evaluation. Twenty-seven substituted isophthalonitriles, 19 trimesonitriles, 30 benzonitriles, and 16 terephthalonitriles were tested in the rat utilizing the carrageenan-induced pedal edema assay. Based on the performance of phenylbutazone in this assay (43.8% reduction at 100 mg/kg), six compounds, dosed at 50 mg/kg, produced reductions in inflammation comparable to this standard. However, the LD50 value of each compound dosed at this level was in the range of 40-56 mg/kg in the mouse; therefore, further study was not warranted. Fifteen compounds possessed activity in excess of 20% reduction at 200 mg/kg and also possessed LD50 values greater than 300 mg/kg. Of these cyanobenzenes, trimesonitrile, 4-chlorobenzonitrile, 2-chloroterephthalonitrile, and 2-fluoroterephthalonitrile with reductions in edema of 32, 30, 46, and 49%, respectively, represent the best candidates for subsequent study.