57538-75-7

Basic information

• Product Name: O-[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl] hydrogen phosphorofluoridate
• Synonyms: O-[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl] hydrogen phosphorofluoridate
• CAS NO: 57538-75-7
• Molecular Weight: 626.575
• Mol File: 57538-75-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: O-[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl] hydrogen phosphorofluoridate(CAS DataBase Reference)
• NIST Chemistry Reference: O-[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl] hydrogen phosphorofluoridate(57538-75-7)
• EPA Substance Registry System: O-[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl] hydrogen phosphorofluoridate(57538-75-7)

Safety Data

• Hazardous Substances Data: 57538-75-7(Hazardous Substances Data)

Upstream product

• 171081-12-2 O-[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl] O-(2-cyanoethyl) phosphorofluoridite 
• 40615-39-2 5'-O-(4-4'-dimethoxytrityl)thymidine 
• 171081-10-0 O-(5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl) O-(tert-butyl) phosphorofluoridite 
• 162611-40-7 5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl-(N,N-diisopropylamino)phosphorofluoridite 
• 153413-66-2 O-(5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl) O-(4-nitrophenyl) N,N-diisopropylphosphoramidite 
• 171081-16-6 O-[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl] O-(2-cyanoethyl) phosphorofluoridate 
• 171081-14-4 O-(5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl) O-(tert-butyl) phosphorofluoridate 

Relevant articles and documents

Synthesis of phosphorofluoridates and phosphorofluoridothioates via the phosphoramidite approach

We present a very efficient synthetic procedure leading to the phosphorofluoridates RO-P(O)(OH)F 1 or phosphorofluoridothioates RO-P(S)(OH)F 2, which is based on the intermediary of fluorophosphoramidites (RO)P(F)N iPr2 5 [R = 9-(hyd

First Synthesis of Nucleosidyl Phosphorofluoridothioates and a Convenient Synthesis of Nucleosidyl Phosphorofluoridates

The first synthesis of 3'- or 5'-nucleosidyl phosphorofluoridothioates RO-P(S)(OH)F have been accomplished via nucleosidyl phosphoramidofluoridates RO-P(NPr12)F.An analogous convenient procedure has been employed to prepare 3'- or 5'-nucleosidy