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5758-63-4

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  • (8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-iodoacetyl)-10,13-dimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione

    Cas No: 5758-63-4

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  • (8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-iodoacetyl)-10,13-dimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione cas 5758-63-4

    Cas No: 5758-63-4

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5758-63-4 Usage

Type of Compound

Organic compound

Molecular Weight

522.4 g/mol

Appearance

White crystalline powder

Solubility

Soluble in water, slightly soluble in ethanol, and practically insoluble in nonpolar solvents

Medical Applications

a. Radiocontrast agent for X-rays and CT scans
b. Visualization of gallbladder, bile ducts, and urinary system
c. Treatment of hyperthyroidism by blocking thyroid hormone production

Mechanism of Action

Absorbs X-rays to provide contrast in medical imaging

Additional Studies

Potential use in cancer treatment and as a contrast agent for brain and spinal cord imaging

Safety Precautions

May cause allergic reactions, gastrointestinal disturbances, and other side effects; contraindicated in patients with a history of iodine allergy or hypersensitivity

Regulatory Status

Approved by the FDA for use as a radiocontrast agent and in the treatment of hyperthyroidism

Storage

Store in a tightly closed container, protected from light, and at room temperature

Stability

Stable under normal conditions, but may degrade upon exposure to heat, light, or moisture

Environmental Impact

Classified as a hazardous substance due to its potential environmental and health risks; proper disposal and handling are required

Synonyms

Telepaque, Iopamidol, Iopamiron

Chemical Structure

A steroidal compound with a 21-iodo substituent, a 17-hydroxy group, and a 3,11,20-trione functionality

Synthesis

Typically synthesized through a series of chemical reactions starting from a steroidal precursor, such as pregnenolone or progesterone

Check Digit Verification of cas no

The CAS Registry Mumber 5758-63-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,7,5 and 8 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 5758-63:
(6*5)+(5*7)+(4*5)+(3*8)+(2*6)+(1*3)=124
124 % 10 = 4
So 5758-63-4 is a valid CAS Registry Number.

5758-63-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name (8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-iodoacetyl)-10,13-dimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione

1.2 Other means of identification

Product number -
Other names 17-hydroxy-19-nor-pregn-4-ene-3,20-dione

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5758-63-4 SDS

5758-63-4Relevant articles and documents

Amino- and dienamino-derivatives formed from adrenocortical steroids and heterocyclic bases.

Rapi,Ginanneschi,Martinelli,Chelli

, p. 502 - 507 (1972)

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