57660-12-5

Basic information

• Product Name: Benzene, 1,1'-(3,3-dichloro-1,2-diethyl-1,2-cyclopropanediyl)bis[4-methoxy-, trans-
• CAS NO: 57660-12-5
• Molecular Formula: C21H24Cl2O2
• Molecular Weight: 379.326
• Mol File: 57660-12-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzene, 1,1'-(3,3-dichloro-1,2-diethyl-1,2-cyclopropanediyl)bis[4-methoxy-, trans-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,1'-(3,3-dichloro-1,2-diethyl-1,2-cyclopropanediyl)bis[4-methoxy-, trans-(57660-12-5)
• EPA Substance Registry System: Benzene, 1,1'-(3,3-dichloro-1,2-diethyl-1,2-cyclopropanediyl)bis[4-methoxy-, trans-(57660-12-5)

Safety Data

• Hazardous Substances Data: 57660-12-5(Hazardous Substances Data)

Upstream product

• 67-66-3 chloroform 
• 130-79-0 Diethylstilbestrol dimethyl ether 

Downstream Products

• 84608-97-9 trans-<4,4'-(1,2-diethyl-1,2-cyclopropanediyl) bis (phenyl)>-diacetate 
• 57660-13-6 trans-<4,4'-(3,3-dichloro-1,2-diehyl-1,2-cyclopropanediyl) bis (phenyl)>-diacetate 
• 57660-16-9 trans-1,2-diethyl-1,2-bis-(4-methoxyphenyl)cyclopropane 

Relevant articles and documents

Synthesis of clyclopropyl analogs of stilbene and stilbenediol as possible antiestrogens.

Conformationally rigid analogs of stilbene and stilbenediol were prepared via gem-dichlorocyclopropyl precursors utilizing two different synthetic methods: a two-phase catalytic method and an organomercurial method. These precursors were reduced to the corresponding cyclopropyl analogs using sodium and methanol. All compounds are being tested to discriminate between estrogenic and antiestrogenic ability, to determine estrogen binding ability, and to evaluate tissue culture anticancer activity.