577-37-7

Basic information

• Product Name: Aphylline
• Synonyms: Aphylline;(7R)-1,3,4,7,7aβ,8,9,10,11,13,14,14aα-Dodecahydro-7α,14α-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-6-one;10-Oxosparteine;d-Aphylline
• CAS NO: 577-37-7
• Molecular Formula: C15H24N2O
• Molecular Weight: 248.36386
• Mol File: 577-37-7.mol
• Article Data: 6

Chemical Properties

• Melting Point: 52-57°
• Boiling Point: bp4 200°
• Flash Point: 172.7°C
• Appearance: /
• Density: 0.9789 (rough estimate)
• Vapor Pressure: 1.67E-06mmHg at 25°C
• Refractive Index: 1.5286 (estimate)
• CAS DataBase Reference: Aphylline(CAS DataBase Reference)
• NIST Chemistry Reference: Aphylline(577-37-7)
• EPA Substance Registry System: Aphylline(577-37-7)

Safety Data

• Hazardous Substances Data: 577-37-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H24N2O/c18-15-12-9-11(13-5-2-4-8-17(13)15)10-16-7-3-1-6-14(12)16/h11-14H,1-10H2/t11-,12-,13-,14+/m1/s1

Upstream product

• 15333-66-1 (9aR)-3c-((S)-[2]piperidyl)-(9ar)-octahydro-quinolizin-1c-carboxylic acid ; dihydrochloride 
• 643-32-3 (7R)-(7at)-3,4,7,7a,8,9,10,11,13,14-decahydro-2H-7r,14c-methano-dipyrido[1,2-a;1',2'-e][1,5]diazocin-6-one 
• 28031-08-5 (9aR)-3c-((S)-[2]piperidyl)-(9ar)-octahydro-quinolizin-1c-carboxylic acid 
• 124223-08-1 (7ac)-3,4,7,7a,8,9,10,11,13,14-decahydro-2H-7r,14c-methano-dipyrido[1,2-a;1',2'-e][1,5]diazocin-6-one 
• 54401-82-0 4-oxo-3-pyridin-2-yl-4H-quinolizine-1-carboxylic acid ethyl ester 
• 90-39-1 (+-)-sparteine 
• 2739-98-2 ethyl 2-(pyridinyl-2)acetate 
• 489-54-3 (+/-)-(7ac,14ac)-dodecahydro-7r,14c-methano-dipyrido[1,2-a;1',2'-e][1,5]diazocine-6,13-dione 
• 643-90-3 [(9aRS)-3c-((RS)-[2]piperidyl)-(9ar)-octahydro-quinolizin-1c-yl]-methanol 
• 90-39-1 sparteine 
• 90-39-1 (-)-sparteine 
• 90-39-1 (-)-l-sparteine 
• 6376-21-2 lupanine perchlorate 
• 642-67-1 aphyllinic acid 

Downstream Products

• 489-54-3 6,13-Dioxo-spartein 
• 489-72-5 (-)-17-oxosparteine 
• 117634-60-3 17-phenyl-16,17-dehydrosparteinium hydroxide 

Relevant articles and documents

Visible-Light-Mediated Efficient Metal-Free Catalyst for α-Oxygenation of Tertiary Amines to Amides

A metal-free system has been discovered for the efficient α-oxygenation of tertiary amines to the corresponding amides using oxygen as an oxidant. This visible-light-mediated oxygenation reaction exhibited excellent substrates scope under mild reaction conditions and generated water as the only byproduct. The synthetic utility of this approach has been demonstrated by applying onto drug molecules. At the end, detailed mechanistic reactions clearly showed the role of oxygen and the photocatalyst.

Biosynthesis of the lupine alkaloids. II. Sparteine and lupanine

-

SYNTHESES AND INVESTIGATIONS BASED ON APHYLLINIC ACID

-