577-38-8

Basic information

• Product Name: FLAVANOMAREIN
• Synonyms: TRIHYDROXYFLAVANONE;7-O-GLUCOSYL-4',5',8-TRIHYDROXYFLAVANONE;3',4',7,8-TETRAHYDROXYFLAVANONE-7-O-GLUCOSIDE;FLAVANOMAREIN;ISOOKANIN-7-GLUCOSIDE;ISOOKANIN-7-O-GLUCOSIDE;(S)-2-(3,4-dihydroxyphenyl)-7-(beta-D-glucopyranosyloxy)-2,3-dihydro-8-hydroxy-4H-1-benzopyran-4-one;FLAVANOMAREIN WITH HPLC
• CAS NO: 577-38-8
• Molecular Formula: C21H22O11
• Molecular Weight: 450.39
• EINECS: 209-411-1
• Product Categories: Flavanones;reagent
• Mol File: 577-38-8.mol
• Article Data: 0

Chemical Properties

• Melting Point: 243-246°C
• Boiling Point: 818.2±65.0 °C(Predicted)
• Appearance: /
• Density: 1.665±0.06 g/cm3(Predicted)
• PKA: 7.58±0.40(Predicted)
• CAS DataBase Reference: FLAVANOMAREIN(CAS DataBase Reference)
• NIST Chemistry Reference: FLAVANOMAREIN(577-38-8)
• EPA Substance Registry System: FLAVANOMAREIN(577-38-8)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 577-38-8(Hazardous Substances Data)

Usage

Chemical Properties

Flavanomarein, known as isookanin-7-o-glucoside, is a dihydroflavonoid isolated from the ethanolic extract of Coreopsistinctoria and is considered to be one of the active ingredients of the herb with a wide range of pharmacological effects, but there are not many studies on the in vitro and in vivo pharmacokinetics of flavanomarein.

Uses

Flavanomarein is a predominant flavonoid of Coreopsis tinctoria Nutt with protective effects against diabetic nephropathy. Flavanomarein has good antioxidative, antidiabetic, antihypertensive and anti-hyperlipidemic activities.Flavanomarein inhibits high glucose-stimulated epithelialmesenchymal transition in HK-2 cells via targeting spleen tyrosine kinase