57705-16-5Relevant articles and documents
Synthesis of biaryls, fluorenones, cyclopenta[def]phenanthren-4-ones, and benzophenones based on formal [3+3] cyclocondensations of 1,3-bis(silyloxy)buta- 1,3-dienes with 3-(silyloxy)-2-en-1-ones
Reim, Stefanie,Lau, Matthias,Adeel, Muhammad,Hussain, Ibrar,Yawer, Mirza A.,Riahi, Abdolmajid,Ahmed, Zafar,Fischer, Christine,Reinke, Helmut,Langer, Peter
experimental part, p. 445 - 463 (2009/07/25)
Functionalized fluorenones were efficiently prepared in four steps. The [3+3] cyclization of 1,3-bis(silyloxy)buta-1,3- dienes with 3-(silyloxy)-2-en-1- ones afforded salicylates that were transformed into their enol triflates. The Suzuki cross-coupling r
A Novel Cycloaromatization Reaction. Regiocontrolled Synthesis of Substituted Methyl Salicylates
Chan, Tak-Hang,Brownbridge, Peter
, p. 3534 - 3538 (2007/10/02)
A new method of constructing six-membered rings, involving the condensation of two three-carbon units, one with two nucleophilic sites and the other containing two electrophilic sites, is reported.The regiochemistry of the reaction is controlled by the differential reactivities of these sites. 1,3-Bis(trimethylsiloxy)-1-methoxybuta-1,3-diene (1) constitutes the three-carbon fragment with two nucleophilic sites.Condensation of 1 with various equivalents of β-dicarbonyl compounds and titanium tetrachloride gave substituted methyl salicylates.The regiochemistry is controlled by the order of reactivity of the electrophilic sites, which is conjugate position of enone > ketone > monothioacetal, acetal.