5775-74-6

Basic information

• Product Name: (NZ)-N-(3-methylbutylidene)hydroxylamine
• Synonyms: (NZ)-N-(3-methylbutylidene)hydroxylamine;Butanal, 3-methyl-, oxime, (E)-
• CAS NO: 5775-74-6
• Molecular Formula: C₅H₁₁NO
• Molecular Weight: 101.14694
• Mol File: 5775-74-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 158°Cat760mmHg
• Flash Point: 71.4°C
• Appearance: /
• Density: 0.89g/cm³
• PKA: 10.82±0.11(Predicted)
• CAS DataBase Reference: (NZ)-N-(3-methylbutylidene)hydroxylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (NZ)-N-(3-methylbutylidene)hydroxylamine(5775-74-6)
• EPA Substance Registry System: (NZ)-N-(3-methylbutylidene)hydroxylamine(5775-74-6)

Safety Data

• Hazardous Substances Data: 5775-74-6(Hazardous Substances Data)

Usage

Description

(NZ)-N-(3-methylbutylidene)hydroxylamine is an organic compound with the chemical structure featuring a hydroxylamine group and a 3-methylbutylidene group. It is known for its unique properties and potential applications in various industries.

Uses

Used in Floral Fragrance Industry:
(NZ)-N-(3-methylbutylidene)hydroxylamine is used as a floral volatile compound for [application reason]. It is released by certain plants in response to predation, contributing to the overall scent profile of the plant and potentially playing a role in attracting pollinators or deterring predators.
Used in Chemical Synthesis:
(NZ)-N-(3-methylbutylidene)hydroxylamine can be used as a synthetic building block for [application reason]. Its unique structure allows it to be a valuable intermediate in the synthesis of various complex organic molecules, including pharmaceuticals, agrochemicals, and specialty chemicals.
Used in Analytical Chemistry:
(NZ)-N-(3-methylbutylidene)hydroxylamine may be used as a reagent or analytical standard for [application reason]. Its distinct chemical properties can be exploited in the development of new analytical methods or for the calibration of instruments in various research and quality control applications.

Upstream product

• 590-86-3 isovaleraldehyde 

Downstream Products

• 138165-75-0 N-Boc-L-β-homoleucine 

Relevant articles and documents

Discovery of Second Generation RORγ Inhibitors Composed of an Azole Scaffold

Starting from a previously reported RORγ inhibitor (1), successive efforts to improve in vivo potency were continued. Introduction of metabolically beneficial motifs in conjunction with scaffold hopping was examined, resulting in discovery of the second generation RORγ inhibitor composed of a 4-(isoxazol-3-yl)butanoic acid scaffold (24). Compound 24 achieved a 10-fold improvement in in vivo potency in a mouse CD3 challenge model along with significant anti-inflammatory effects in a mouse dermatitis model.

Indolyl-3-acetaldoxime dehydratase from the phytopathogenic fungus Sclerotinia sclerotiorum: Purification, characterization, and substrate specificity

The purification and characterization of indolyl-3-acetaldoxime dehydratase produced by the plant fungal pathogen Sclerotinia sclerotiorum is described. The substrate specificity indicates that it is an indolyl-3-acetaldoxime dehydratase (IAD, EC 4.99.1.6), which catalyzes transformation of indolyl-3-acetaldoxime to indolyl-3-acetonitrile. The enzyme showed Michaelis-Menten kinetics and had an apparent molecular mass of 44 kDa. The amino acid sequence of IAD, determined using LC-ESI-MS/MS, identified it as the protein SS1G-01653 from S. sclerotiorum. IADSs was highly homologous (84% amino acid identity) to the hypothetical protein BC1G-14775 from Botryotinia fuckeliana B05.10. In addition, similarity to the phenylacetaldoxime dehydratases from Gibberella zeae (33% amino acid identity) and Bacillus sp. (20% amino acid identity) was noted. The specific activity of IADSs increased about 17-fold upon addition of Na2S2O4 under anaerobic conditions, but in the absence of Na2S2O 4 no significant change was observed, whether aerobic or anaerobic conditions were used. As with other aldoxime dehydratases isolated from microbes, the role of IADSs in fungal plant pathogens is not clear, but given its substrate specificity, it appears unlikely that IADSs is a general xenobiotic detoxifying enzyme.