57772-67-5Relevant articles and documents
A novel versatile phosphoramidite building block for the synthesis of 5′- and 3′-hydrazide modified oligonucleotides
Antsypovich, Sergey I.,Von Kiedrowski, Guenter
, p. 211 - 226 (2005)
We introduce a novel versatile phosphoramidite building block for the modification of oligonucleotides (ONs) with acyl hydrazides on the 5′- or 3′-terminus, or both. The reaction of these hydrazide functionalized ONs with 4-methoxyphenylaldehyde is demons
Facile folding of insulin variants bearing a prosthetic C-peptide prepared by α-ketoacid-hydroxylamine (KAHA) ligation
Boross, Gábor N.,Shimura, Satomi,Besenius, Melissa,Tennagels, Norbert,Rossen, Kai,Wagner, Michael,Bode, Jeffrey W.
, p. 8388 - 8395 (2018/11/24)
The chemical synthesis of insulin is an enduring challenge due to the hydrophobic peptide chains and construction of the correct intermolecular disulfide pattern. We report a new approach to the chemical synthesis of insulin using a short, traceless, pros
