577777-20-9

Basic information

• Product Name: 3-BOC-3-METHYLAMINOAZATIDINE
• Synonyms: 3-BOC-3-METHYLAMINOAZATIDINE;3-BOC-3-METHYLAMINOAZETIDINE;3-boc-3-methlaminoazatidine;Azetidin-3-ylmethyl-carbamic acid tert-butyl ester HCl;tert-Butyl azetidin-3-yl(methyl)carbamate hydrochloride;3-MethylaMino-3-Boc-azetidine;3-Boc-3-methylamino azetidine hydrochloride;tert-butyl N-(azetidin-3-ylMethyl)carbaMate
• CAS NO: 577777-20-9
• Molecular Formula: C₉H₁₈N₂O₂
• Molecular Weight: 186.25142
• EINECS: 1312995-182-4
• Mol File: 577777-20-9.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 285.5 °C at 760 mmHg
• Flash Point: 126.5 °C
• Appearance: /
• Density: 1.018 g/cm³
• Storage Temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C
• PKA: 10.21±0.40(Predicted)
• Water Solubility: Soluble in water. (5 g/100ml)
• CAS DataBase Reference: 3-BOC-3-METHYLAMINOAZATIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BOC-3-METHYLAMINOAZATIDINE(577777-20-9)
• EPA Substance Registry System: 3-BOC-3-METHYLAMINOAZATIDINE(577777-20-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 577777-20-9(Hazardous Substances Data)

Usage

Uses

It is used as pharmaceutical intermediate.

Upstream product

• 854038-91-8 N-(1-benzhydrylazetidin-3-yl)-N-methylcarbamic acid tert-butyl ester 

Downstream Products

• 1161825-50-8 tert-butyl 1-(2-amino-6-(benzyloxymethyl)pyrimidin-4-yl)-azetidin-3-yl(methyl)carbamate 
• 1429645-07-7 C₂₁H₂₀N₄O₂ 

Relevant articles and documents

2H-PYRAZOLO [4,3-D]PYRIMIDIN-5-AMINE DERIVATIVES AS H4 HISTAMINE RECEPTOR ANTAGONISTS FOR THE TREATMENT OF ALLERGIC, IMMUNOLOGICAL AND INFLAMMATORY DISEASES

Pyrazolopyrimidine derivatives of formula (I), wherein the meaning of the different substituents are those indicated in the description. These compounds are useful as histamine H4 receptor antagonists.

2 -AMINOPYRIMIDINE DERIVATIVES AS HISTAMINE H4 ANTAGONISTS

2-Amino-pyrimidine derivatives of formula I, wherein the meaning of the different substituents are those indicated in the description. These compounds are useful as histamine receptor H4antagonists.

Macrocyclic Spiro Pyrimidine Derivatives

Macrocyclic spiro pyrimidine compounds, compositions comprising such compounds, methods for making the compounds, and methods of treating and preventing the progression of diseases, conditions, and disorders using such compounds and compositions are described herein.