578-16-5 Usage
General Description
2',4'-Dimethoxy-2,2,2-trifluoroacetophenone is a chemical compound with the molecular formula C10H10F3O3. It is a fluoro-substituted acetophenone derivative, containing two methoxy groups and three fluorine atoms attached to the benzene ring. 2',4'-DIMETHOXY-2,2,2-TRIFLUOROACETOPHENONE is commonly used as a reagent in organic synthesis, particularly in the preparation of heterocyclic compounds and pharmaceutical intermediates. It is also a versatile building block in the synthesis of various functional materials and advanced organic molecules. Its unique combination of functional groups and reactivity makes it a valuable and widely used chemical in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 578-16-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,7 and 8 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 578-16:
(5*5)+(4*7)+(3*8)+(2*1)+(1*6)=85
85 % 10 = 5
So 578-16-5 is a valid CAS Registry Number.
578-16-5Relevant articles and documents
CoCl2 catalyzed trifluoroacetylation versus dimerization of methoxyaromatics using trifluoroacetic anhydride
Ruiz, Jaime,Astruc, Didier,Gilbert, Laurent
, p. 4511 - 4514 (1996)
Anisole, resorcinol dimethyl ether, p methylanisole, and β- methoxynaphthalene undergo regiospecific trifluoroacetylation in neat influoroacetic anhydride (TFAA) at 100 °C in the presence of 0.1 eq. CoCl2 as catalyst, with a 1:1 anisole/TFAA ra
Catalytic asymmetric hydrogenation of α-CF3- or β-CF3-Substituted acrylic acids using Rhodium(I) complexes with a combination of chiral and achiral ligands
Dong, Kaiwu,Li, Yang,Wang, Zheng,Ding, Kuiling
supporting information, p. 14191 - 14195 (2014/01/06)
Only the mixture works! Acrylic acid derivatives with CF3 substituents in α or β position were efficiently hydrogenated in the presence of a RhI complex with a chiral secondary phosphine oxide (SPO; see scheme) and an achiral Ph3P as ligands. The corresponding propanoic acid derivatives were obtained with generally high conversion (>99 %) and high enantioselectivity (92->99 %). Copyright
