57814-09-2Relevant articles and documents
A mild and chemoselective CALB biocatalysed synthesis of sulfoxides exploiting the dual role of AcOEt as solvent and reagent
Anselmi, Silvia,Liu, Siyu,Kim, Seong-Heun,Barry, Sarah M.,Moody, Thomas S.,Castagnolo, Daniele
supporting information, p. 156 - 161 (2021/01/14)
A mild, chemoselective and sustainable biocatalysed synthesis of sulfoxides has been developed exploiting CALB and using AcOEt with a dual role of more environmentally friendly reaction solvent and enzyme substrate. A series of sulfoxides, including the drug omeprazole, have been synthesised in high yields and with excellent E-factors.
Synthesis of compounds with juvenile hormone activity; XXXI: Stereocontrolled synthesis of (+)-juvabione from a chiral sulfoxide
Watanabe,Shimizu,Mori
, p. 1249 - 1254 (2007/10/02)
A stereocontrolled synthesis of (+)-juvabione is described. The key step is a regioselective lithiation of a chiral (E)-butenyl sulfoxide 5 followed by stereoselective 1,4-addition to cyclohex-2-en-1-one. The chiral sulfoxide 5 was prepared by employing a
Sodium Telluride-Mediated Sulfenylation of α-Halo Carbonyl Compounds with Diphenyl Disulfide
Padmanabhan, Seetharamaiyer,Ogawa, Takuji,Suzuki, Hitomi
, p. 1358 - 1360 (2007/10/02)
Under mild aprotic conditions α-halo carbonyl compounds react with diphenyl disulfide in the presence of sodium telluride to give the corresponding α-phenylthio derivatives in good to moderate yields.The reaction appears to proceed involving the sulfur-sulfur bond cleavage of diphenyl disulfide by sodium telluride.
