5798-76-5

Basic information

• Product Name: Benzoic acid, 4-broMo-, phenyl ester
• Synonyms: Benzoic acid, 4-broMo-, phenyl ester
• CAS NO: 5798-76-5
• Molecular Formula: C₁₃H₉BrO₂
• Molecular Weight: 277.11336
• Mol File: 5798-76-5.mol
• Article Data: 35

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzoic acid, 4-broMo-, phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-broMo-, phenyl ester(5798-76-5)
• EPA Substance Registry System: Benzoic acid, 4-broMo-, phenyl ester(5798-76-5)

Safety Data

• Hazardous Substances Data: 5798-76-5(Hazardous Substances Data)

Upstream product

• 4773-12-0 diphenyl sulfite 
• 586-76-5 4-Bromobenzoic acid 
• 586-75-4 4-chlorobenzoyl chloride 
• 108-95-2 phenol 
• 1633-33-6 4-bromobenzoic anhydride 
• 201230-82-2 carbon monoxide 
• 589-87-7 1,4-bromoiodobenzene 
• 13360-92-4 phenyl diphenylphosphinite 
• 2996-92-1 phenyl trimethylsiloxane 
• 1242438-10-3 O-(4-bromophenyl) O-phenyl thiocarbonate 
• 1122-91-4 4-bromo-benzaldehyde 
• 98-80-6 phenylboronic acid 
• 71-43-2 benzene 
• 1005-56-7 phenylcarbonochloridothioate 

Downstream Products

• 5933-32-4 4-bromobenzoic acid hydrazide 
• 866849-59-4 phenyl 4-(3-phenoxyprop-1-ynyl)benzoate 
• 760990-49-6 2-(4-bromobenzoyl)-5,6-dimethoxy-indan-1-one 
• 760994-54-5 6-(benzyloxy)-2-(4-bromobenzoyl)-5-methoxyindan-1-one 
• 760990-50-9 C₁₈H₁₅BrN₂O₂ 
• 760994-55-6 7-(benzyloxy)-3-(4-bromophenyl)-6-methoxy-1,4-dihydroindeno[1,2-c]pyrazole 

Relevant articles and documents

Conversion of esters to thioesters under mild conditions

We report conversion of esters to thioestersviaselective C-O bond cleavage/weak C-S bond formation under transition-metal-free conditions. The method is notable for a general and practical transition-metal-free system, broad substrate scope and excellent functional group tolerance. The strategy was successfully deployed in late-stage thioesterification, site-selective cross-coupling/thioesterification/decarbonylation and easy-to-handle gram scale thioesterification. Selectivity and computational studies were performed to gain insight into the formation of weak C-S bonds by C-O bond cleavage, which contrasts with the traditional trend of nucleophilic additions to carboxylic acid derivatives.

Mechanically induced solvent-free esterification method at room temperature

Herein, we describe two novel strategies for the synthesis of esters, as achieved under high-speed ball-milling (HSBM) conditions at room temperature. In the presence of I2 and KH2PO2, the reactions afford the desired esterification derivatives in 45% to 91% yields within 20 min of grinding. Meanwhile, using KI and P(OEt)3, esterification products can be obtained in 24% to 85% yields after 60 min of grinding. In addition, the I2/KH2PO2 protocol was successfully extended to the late-stage diversification of natural products showing the robustness of this useful approach. Further application of this method in the synthesis of inositol nicotinate was also discussed. This journal is

Design and Bioevaluation of Novel Hydrazide-Hydrazones Derived from 4-Acetyl-N-Substituted Benzenesulfonamide

Abstract: In this research, a series of hydrazine-hydrazone derivatives (Ia–g), (IIa–h) were synthesized to discover new antioxidant and anticholinesterase agents. The structures of synthesized compounds were characterized by spectroscopic data using UV, IR, 1H, 13C NMR, mass spectroscopy, and elemental analysis. The bio-evaluation of the synthesized compounds (Ia–g), (IIa–h) were evaluated according to in vitro activity assays. The results of β-carotene/linoleic acid assay showed that among the synthesized compounds, the (Ib), (Ie), (IIb–IIe), and (IIh) compound exhibited higher activity for the lipid peroxidation inhibitory activity. In the DPPH free scavenging activity and the cation radical scavenging activity in ABTS?+ activity, compound (IIb) was found to be more active. In the CUPRAC reduced power assay, the A0.5 values of all synthesized compounds were better than α-TOC. In AChE assay, compound (IIb) exhibited the most activity with IC50 = 11.12 ± 0.74 μM, while the compounds (Ib–g) and (IIb–h), exhibited excellent activity than the positive standard galantamine (IC50 = 46.06 ± 0.10 μM) in the BChE assay.