57987-77-6

Basic information

• Product Name: 7,8-dichloro-1,2,3,4-tetrahydroisoquinolinium chloride
• Synonyms: 7,8-dichloro-1,2,3,4-tetrahydroisoquinolinium chloride;7,8-dichloro-1,2,3,4-tetrahydroisoquinoline;SKF-64139;7,8-dichloro-1,2,3,4-tetrahydroisoquinoline hydrochloride
• CAS NO: 57987-77-6
• Molecular Formula: C₉H₉Cl₂N*ClH
• Molecular Weight: 238.5414
• EINECS: 261-064-5
• Mol File: 57987-77-6.mol
• Article Data: 7

Chemical Properties

• Melting Point: 225-227 °C(Solv: methanol (67-56-1); ethyl ether (60-29-7))
• Boiling Point: 310.7°Cat760mmHg
• Flash Point: 141.7°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 0.000589mmHg at 25°C
• CAS DataBase Reference: 7,8-dichloro-1,2,3,4-tetrahydroisoquinolinium chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 7,8-dichloro-1,2,3,4-tetrahydroisoquinolinium chloride(57987-77-6)
• EPA Substance Registry System: 7,8-dichloro-1,2,3,4-tetrahydroisoquinolinium chloride(57987-77-6)

Safety Data

• Hazardous Substances Data: 57987-77-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H9Cl2N.ClH/c10-8-2-1-6-3-4-12-5-7(6)9(8)11;/h1-2,12H,3-5H2;1H

Upstream product

• 61563-45-9 2-acetyl-7,8-dichloro-1,2,3,4-tetrahydroisoquinoline 
• 74819-76-4 2-(2,3,-dichlorobenzylamino) 1-ethanol hydrochloride 
• 61563-36-8 7,8-dichloroisoquinoline 
• 61563-24-4 7,8-dichloro-1,2,3,4-tetrahydroisoquinoline 
• 6334-18-5 2,3-dichlorobenzylaldehyde 
• 57987-75-4 2,3-dichloro-N-(2,2-dimethoxyethyl)benzylidenamine 
• 57987-75-4 N-<(2,3-dichlorophenyl)methylene>-2,2-dimethoxyethanamine 
• 73261-85-5 2-acetyl-7,8-dichloro-1,2-dihydroisoquinoline 
• 73261-79-7 N-(2,3-dichlorobenzyl)-N-(2,2-dimethoxyethyl)acetamide 

Downstream Products

• 79-07-2 Chloroacetamide 

Relevant articles and documents

Method for preparing tetrahydroisoquinolines

A method for preparing 1,2,3,4-tetrahydroisoquinolines comprising heating N-halo or hydroxyethyl-N-benzylamines in an aluminum chloride melt at 160°-210°.

Facile synthesis of halo-substituted tetrahydroisoquinolines and tetrahydro-2-benzazepines via N-acetyl-1,2-dihydroisoquinolines

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INTRAMOLECULAR FRIEDEL-CRAFTS ALKYLATIONS. II. AN EFFICIENT SYNTHESIS OF BIOLOGICALLY ACTIVE 1,2,3,4-TETRAHYDROISOQUINOLINES

A new synthesis of tetrahydroisoquinolines bearing electron withdrawing groups is presented.The scope and mechanism of the reaction are discussed.Many of these tetrahydroisoquinolines are potent inhibitors of the enzyme PNMT.