5801-17-2

Basic information

• Product Name: 2-[2-(4-methoxyphenyl)-5-phenyl-1H-imidazol-4-yl]-9H-fluoren-9-one
• Synonyms: 9H-fluoren-9-one, 2-[2-(4-methoxyphenyl)-5-phenyl-1H-imidazol-4-yl]-
• CAS NO: 5801-17-2
• Molecular Formula: C₁₀H₁₃Br
• Molecular Weight: 428.4813
• Mol File: 5801-17-2.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 687°C at 760 mmHg
• Flash Point: 369.3°C
• Density: 1.274g/cm³
• Vapor Pressure: 9.97E-19mmHg at 25°C
• Refractive Index: 1.678
• CAS DataBase Reference: 2-[2-(4-methoxyphenyl)-5-phenyl-1H-imidazol-4-yl]-9H-fluoren-9-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[2-(4-methoxyphenyl)-5-phenyl-1H-imidazol-4-yl]-9H-fluoren-9-one(5801-17-2)
• EPA Substance Registry System: 2-[2-(4-methoxyphenyl)-5-phenyl-1H-imidazol-4-yl]-9H-fluoren-9-one(5801-17-2)

Safety Data

• Hazardous Substances Data: 5801-17-2(Hazardous Substances Data)

Usage

Chemical structure

2-[2-(4-methoxyphenyl)-5-phenyl-1H-imidazol-4-yl]-9H-fluoren-9-one consists of a fluorenone core, a 1H-imidazole ring, and a methoxyphenyl and phenyl substituent.

Potential applications

This compound has potential applications in pharmaceutical and chemical research due to its unique structural features.

Biological activity

It may exhibit biological activity, making it of interest for medicinal chemistry efforts.

Development of new drug candidates

The synthesis and study of this compound could lead to the development of new drug candidates.

Potential applications in various industries

The compound's properties and structure could lead to the creation of materials with a range of potential applications across different industries.

Upstream product

• 2722-36-3 3-phenyl-1-butanol 
• 107-80-2 1,3-dibromobutane 
• 71-43-2 benzene 
• 13950-05-5 α-Methylbenzyllithium 
• 81171-82-6 (3-phenylbutyl)trichlorosilane 
• 3461-50-5 methyl trans-3-methylcinnamate 
• 54976-38-4 (E)-3-phenylbut-2-en-1-ol 
• 98-86-2 acetophenone 
• 4593-90-2 3-phenylbutyric acid 
• 54976-37-3 3-phenylbut-2-en-1-ol 
• 2214-14-4 (1-methylcyclopropyl)benzene 

Downstream Products

• 16113-05-6 4-ethyl-3-(3-phenyl-butyl)-1-oxa-3-aza-spiro[4.4]nonan-2-one 
• 16433-43-5 4-phenyl-1-pentanoic acid 
• 107590-53-4 4-phenylpentanenitrile 
• 93727-19-6 1.4-Diphenyl-pentanol 
• 36617-84-2 (R/S)-N,N-dimethyl-(3-phenylbutyl)amine 
• 40628-91-9 1,4-dimethyl-4-phenyl-1,2,3,4-tetrahydronaphthalene 
• 1520-44-1 1,3-diphenylbutane 
• 86437-09-4 1-Methyl-4-((S)-3-phenyl-butane-1-sulfinyl)-benzene 
• 86437-09-4 (+)-4-methyl-<(-3-phenylbutyl)sulfinyl>-benzene 
• 79409-75-9 (E)-2-Methyl-8-phenyl-5-phenylsulfanyl-5-trimethylsilanyl-non-3-en-2-ol 
• 135-98-8 sec-Butylbenzene 
• 4613-11-0 2,3-diphenylbutane 
• 51193-79-4 1,1-dimethyl-4-phenylpentanol 
• 15197-68-9 4-phenylpentanal 

Relevant articles and documents

Boron tribromide as a reagent for anti-Markovnikov addition of HBr to cyclopropanes

Although radical formation from a trialkylborane is well documented, the analogous reaction mode is unknown for trihaloboranes. We have discovered the generation of bromine radicals from boron tribromide and simple proton sources, such as water ortert-butanol, under open-flask conditions. Cyclopropanes bearing a variety of substituents were hydro- and deuterio-brominated to furnish anti-Markovnikov products in a highly regioselective fashion. NMR mechanistic studies and DFT calculations point to a radical pathway instead of the conventional ionic mechanism expected for BBr3

Intrazeolite photooxygenation of chiral alkenes. Control of facial selectivity by confinement and cation-π interactions

Depending on the nature of the substituents on the stereogenic carbon atom, the ene reaction of singlet oxygen with several chiral alkenes by confinement within thionin-supported zeolite NaY, may exhibit significant changes on facial selectivity by comparison to their photooxygenation reaction in solution. It is proposed that, apart from the conformational consequences as a result of the alkene confinement within the zeolite cavities, a synergism between Na+-π interactions and singlet oxygen-Na+ interactions plays a significant role in the transition states of ene hydroperoxidation. Within NaY, the diastereoselectivity may significantly depend on the site selectivity, as probed through specific deuterium labelling of trisubstituted alkenes bearing a gem-dimethyl group. In certain cases, a remote stereogenic centre relative to the reacting double bond may induce enhanced diastereoselection and regioselectivity.

Ene Reaction Mechanisms. 1. Chirality Transfer to the Enophile 4-Methyl-N-sulfinylbenzenesulfonamide

The ene reaction of (S)-(+)-3-phenyl-1-butene (1) with N-sulfinyl-p-toluenesulfonamide (2) leads to the optically active (E)-2-alkenesulfinamide 3.This corresponds to a chirality transfer from the chiral carbon center in 1 to the sulfur atom of the produc