5803-73-6

Basic information

• Product Name: 6-hydroxy-2-[(4,6,7-trimethylquinazolin-2-yl)amino]pyrimidin-4(3H)-one
• Synonyms: 2-[(4,6,7-Trimethylquinazolin-2-yl)amino]pyrimidine-4,6-diol; 4,6-Pyrimidinediol, 2-[(4,6,7-trimethyl-2-quinazolinyl)amino]-
• CAS NO: 5803-73-6
• Molecular Formula: C₁₄H₁₈O₃
• Molecular Weight: 297.3119
• Mol File: 5803-73-6.mol
• Article Data: 3

Chemical Properties

• Density: 1.45g/cm³
• Refractive Index: 1.718
• CAS DataBase Reference: 6-hydroxy-2-[(4,6,7-trimethylquinazolin-2-yl)amino]pyrimidin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-hydroxy-2-[(4,6,7-trimethylquinazolin-2-yl)amino]pyrimidin-4(3H)-one(5803-73-6)
• EPA Substance Registry System: 6-hydroxy-2-[(4,6,7-trimethylquinazolin-2-yl)amino]pyrimidin-4(3H)-one(5803-73-6)

Safety Data

• Hazardous Substances Data: 5803-73-6(Hazardous Substances Data)

Upstream product

• 5803-71-4 ethyl 2-(5,6,7,8,-tetrahydro-2-naphthyl)-2-oxoacetate 
• 119-64-2 tetralin 

Downstream Products

• 7433-10-5 1-<5.6.7.8-Tetrahydro-naphthyl-(2)>-2-sek.-butylamino-aethanol 
• 77062-86-3 ethyl 2-hydroxy-2-(4-hexylphenyl)acetate 

Relevant articles and documents

Sulfur-containing heterocyclic compounds useful for the treatment of osteoporosis, and their production

The present invention provides a sulfur-containing heterocyclic compound of the formula (I) STR1 wherein ring A is a benzene ring which may be substituted; R is a hydrogen atom or a hydrocarbon group which may be substituted; B is a carboxyl group which may be esterified or amidated; X is --CH(OH)-- or --CO--; k is 0 or 1; and k' is 0, 1 or 2 or a pharmaceutically acceptable salt thereof. Also, it provides a process for producing the compound (I) or a salt thereof and a pharmaceutical preparation for use in the treatment of osteoporosis comprising the compound (I) or salt thereof. The compounds (I) and salts thereof show excellent bone resorption inhibitory activity.

Separation and absolute configuration of the stereoisomers of 2-sec.butylamino-1-(5,6,7,8-tetrahydro-2-naphtyl)ethanol. II. Inhibitors of beta-adrenergic receptors

-