5807-65-8

Basic information

• Product Name: DIETHYL BIPHENYL 2,2'-DICARBOXYLATE
• Synonyms: DIETHYL BIPHENYL 2,2'-DICARBOXYLATE;RARECHEM AL BI 0377;[1,1'-Biphenyl]-2,2'-dicarboxylic acid, diethyl ester;[1,1'-Biphenyl]-2,2'-dicarboxylic acid 2,2'-diethyl ester
• CAS NO: 5807-65-8
• Molecular Formula: C₁₈H₁₈O₄
• Molecular Weight: 298.33
• Mol File: 5807-65-8.mol
• Article Data: 3

Chemical Properties

• Melting Point: 43-44 °C
• Boiling Point: 341.9°Cat760mmHg
• Flash Point: 110.8°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 7.82E-05mmHg at 25°C
• CAS DataBase Reference: DIETHYL BIPHENYL 2,2'-DICARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIETHYL BIPHENYL 2,2'-DICARBOXYLATE(5807-65-8)
• EPA Substance Registry System: DIETHYL BIPHENYL 2,2'-DICARBOXYLATE(5807-65-8)

Safety Data

• Hazardous Substances Data: 5807-65-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C16H27NO.ClH/c1-3-4-17-11(2)15(18)16-8-12-5-13(9-16)7-14(6-12)10-16;/h11-14,17H,3-10H2,1-2H3;1H

Upstream product

• 6091-64-1 2-bromobenzoic acid ethyl ester 
• 64-17-5 ethanol 
• 85-01-8 phenanthrene 
• 1829-28-3 ethyl 2-iodobenzoate 
• 557-20-0 diethylzinc 

Downstream Products

• 5447-75-6 ethyl 9-oxo-9H-fluorene-4-carboxylate 
• 24017-92-3 2'-acetyl-[1,1'-biphenyl]-2-carboxylic acid 
• 56523-95-6 C₇₀H₉₀O₄ 
• 18076-62-5 2,2'-bis(hydroxyldiphenylmethyl)biphenyl 
• 194494-02-5 2,2'-bis[bis(p-methoxyphenyl)hydroxymethyl]biphenyl 
• 655234-98-3 {2'-[bis-(4-fluoro-phenyl)-hydroxy-methyl]-biphenyl-2-yl}-bis-(4-fluoro-phenyl)-methanol 
• 500310-15-6 5,5,7,7-Tetraphenyl-5,7-dihydro-dibenz[c,e]oxepin 
• 127118-01-8 [2'-(Hydroxy-diphenyl-methyl)-biphenyl-2-yl]-diphenyl-methanol; compound with propan-2-one 
• 127118-28-9 [2'-(Hydroxy-diphenyl-methyl)-biphenyl-2-yl]-diphenyl-methanol; compound with 2-methyl-naphthalene 
• 127118-29-0 [2'-(Hydroxy-diphenyl-methyl)-biphenyl-2-yl]-diphenyl-methanol; compound with cyclohexanone 
• 776-35-2 9,10-dihydrophenanthrene 
• 38274-14-5 2,2'-bis-(bromomethyl)-1,1'-biphenyl 
• 875855-78-0 2,2'-bis-(2-hydroxymethyl-phenyl)-bibenzyl 

Relevant articles and documents

Experimental study of the mechanism of the palladium-catalyzed aryl-alkyl negishi coupling using hybrid phosphine-electron-withdrawing olefin ligands

A detailed study of the Negishi cross-coupling reaction of ArI (Ar = 2-C6H4CO2Et) and ZnEt2 with palladium catalysts containing conventional phosphines versus one using a chelating hybrid phosphine-electron-withdrawing olefin (P-EWO) ligand reveals that for conventional phosphines (e.g., PPh3) β-H elimination from intermediate [PdArEt(PPh3)2] is competitive with Ar-Et reductive elimination and is responsible for part of the undesired reduction product ArH. In contrast, with the EWO phosphine, the β-H elimination from intermediate [PdArEt(P-EWO)] is slow compared to the fast Ar-Et reductive elimination, and the undesired reduction product ArH observed proceeds in this case of hydrolysis of ZnArEt, formed in transmetalations where Ar is transferred from Pd to Zn. The rate of these transmetalations is comparable to the rate of reductive eliminations. Consequently, undesired transmetalations affording [PdEt2(P-EWO)] and ZnArEt are more effective at early stages of the reactions and less effective when the ethylating agent becomes poorer in ZnEt2 and richer in ZnEtX (X = I), as the reaction proceeds. Careful analysis of the experiments reveals the detailed changing evolution of the reaction, not only providing the main features of the catalytic cycle but also deducing how the reagents in the system change with time and what the effects on the products of these changes are.

A brand-new Pd-mediated generation of benzyne and its [2+2+2] cycloaddition: δ-carbon elimination and concomitant decarboxylation

We found a brand-new method for the generation of aryne from methyl 2-bromobenzoates via the Pd-mediated concomitant δ-carbon elimination and decarboxylation. The generated arynes underwent Pd-mediated [2+2+2] cycloaddition to give triphenylenes.