581-30-6

Basic information

• Product Name: 3-Phenothiazone
• Synonyms: 3-Phenothiazone;3H-Phenothiazin-3-one
• CAS NO: 581-30-6
• Molecular Formula: C₁₂H₇NOS
• Molecular Weight: 213.25508
• Mol File: 581-30-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 349.3 °C at 760 mmHg
• Flash Point: 165 °C
• Appearance: /
• Density: 1.36g/cm³
• Vapor Pressure: 4.75E-05mmHg at 25°C
• Refractive Index: 1.72
• CAS DataBase Reference: 3-Phenothiazone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Phenothiazone(581-30-6)
• EPA Substance Registry System: 3-Phenothiazone(581-30-6)

Safety Data

• Hazardous Substances Data: 581-30-6(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Synthetic Communications, 20, p. 1543, 1990 DOI: 10.1080/00397919008052871

InChI:InChI=1/C12H7NOS/c14-8-5-6-10-12(7-8)15-11-4-2-1-3-9(11)13-10/h1-7H

Upstream product

• 92-84-2 10H-phenothiazine 
• 58-40-2 promazine 
• 40248-84-8 3-mercaptophenol 

Downstream Products

• 3225-29-4 p-benzosemiquinone radical anion 
• 55847-64-8 2-(4-methoxy-anilino)-phenothiazin-3-one 
• 55847-65-9 2-(N-ethyl-anilino)-phenothiazin-3-one 
• 55847-66-0 7-(N-ethyl-anilino)-phenothiazin-3-one 
• 55847-63-7 2-(4-nitro-anilino)-phenothiazin-3-one 
• 27349-60-6 2-anilino-3H-phenothiazin-3-one 
• 55847-61-5 2,7-dianilino-phenothiazin-3-one 
• 68019-37-4 7-p-tolylsulfanyl-phenothiazin-3-one 
• 68019-38-5 2-p-tolylsulfanyl-phenothiazin-3-one 
• 55847-60-4 7-(N-methyl-anilino)-phenothiazin-3-one 
• 55847-59-1 2-methylanilino-3H-phenothiazin-3-one 
• 98412-06-7 2-m-Tolyloxy-phenothiazin-3-one 
• 98412-10-3 2-(4-Hydroxy-2-methyl-phenyl)-phenothiazin-3-one 
• 98412-09-0 2-hydroxyphenylphenothiazinone-3 

Relevant articles and documents

Biomimetic oxidation of some nitrogen compounds by iodylbenzene plus vanadyl acetylacetonate

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Further studies on the cyclisation of 3-hydroxy-2'-nitrodiphenyl ethers and related compounds

The reductive cyclisation of 4,6-dimethyl and 4,6-dichloro derivatives of 3-hydroxy-2'-nitrodiphenyl ethers has been examined as a potential route to 1H-phenoxazinones. Unexpectedly, cyclisation of the dichloro compound proceeded with loss of a Cl and yielded 2-chloro-3H-phenoxazin-3-one. The cyclisation of a range of analogous substrates has been investigated and shown to provide novel and convenient syntheses of 3-amino-phenoxazine, 3H-phenothiazin-3-one and 8-hydroxy-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one.