581069-45-6

Basic information

• Product Name: 6.7-Methylendioxy-1-<3.4.5-trimethoxy-phenyl>-1.2-dihydro-naphthoesaeure-(2)-methylester
• Synonyms: 6.7-Methylendioxy-1-<3.4.5-trimethoxy-phenyl>-1.2-dihydro-naphthoesaeure-(2)-methylester
• CAS NO: 581069-45-6
• Molecular Weight: 398.412
• Mol File: 581069-45-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6.7-Methylendioxy-1-<3.4.5-trimethoxy-phenyl>-1.2-dihydro-naphthoesaeure-(2)-methylester(CAS DataBase Reference)
• NIST Chemistry Reference: 6.7-Methylendioxy-1-<3.4.5-trimethoxy-phenyl>-1.2-dihydro-naphthoesaeure-(2)-methylester(581069-45-6)
• EPA Substance Registry System: 6.7-Methylendioxy-1-<3.4.5-trimethoxy-phenyl>-1.2-dihydro-naphthoesaeure-(2)-methylester(581069-45-6)

Safety Data

• Hazardous Substances Data: 581069-45-6(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 2675-79-8 1-bromo-3,4,5-trimethoxybenzene 
• 581069-50-3 4-tert-butyl-2-naphtho[2,3-d][1,3]dioxol-6-yl-4,5-dihydro-oxazole 
• 581069-48-9 4-isopropyl-2-naphtho[2,3-d][1,3]dioxol-6-yl-4,5-dihydro-oxazole 
• 107401-98-9 Naphtho[2,3-d][1,3]dioxole-6-carbonitrile 

Downstream Products

• 1028264-41-6 3-(3,4,5-trimethoxy-phenyl)-1a,2,3,8b-tetrahydro-1,5,7-trioxa-cyclopenta[g]cyclopropa[a]naphthalene-2-carboxylic acid methyl ester 
• 4375-07-9 epipodophyllotoxin 
• 4375-06-8 epipicropodophyllotoxin 
• 581069-46-7 (5R,8S)-8-Hydroxy-5-(3,4,5-trimethoxy-phenyl)-5,8-dihydro-naphtho[2,3-d][1,3]dioxole-6-carboxylic acid methyl ester 
• 173524-35-1 (-)-Methyl epipodophyllate 

Relevant articles and documents

Efficient enantioselective total synthesis of (-)-epipodophyllotoxin

In only twelve steps the total synthesis of (-)-epipodophyllotoxin (2) has been completed starting from commercially available piperonal (1). The first stereo-center was formed under auxilary control, while the following epoxidation and radical cyclization proceeded with outstanding diastereoselectivity, which enabled the target molecule to be isolated in an overall yield of 30% and with 97% ee.