581097-13-4

Basic information

• Product Name: 2-Furanmethanol, 5-(6-chloro-2-fluoro-9H-purin-9-yl)-3,3-difluorotetrahydro-, benzoate (ester), (2S)-
• CAS NO: 581097-13-4
• Molecular Formula: C17H12ClF3N4O3
• Molecular Weight: 412.755
• Mol File: 581097-13-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Furanmethanol, 5-(6-chloro-2-fluoro-9H-purin-9-yl)-3,3-difluorotetrahydro-, benzoate (ester), (2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Furanmethanol, 5-(6-chloro-2-fluoro-9H-purin-9-yl)-3,3-difluorotetrahydro-, benzoate (ester), (2S)-(581097-13-4)
• EPA Substance Registry System: 2-Furanmethanol, 5-(6-chloro-2-fluoro-9H-purin-9-yl)-3,3-difluorotetrahydro-, benzoate (ester), (2S)-(581097-13-4)

Safety Data

• Hazardous Substances Data: 581097-13-4(Hazardous Substances Data)

Upstream product

• 1651-29-2 6-chloro-2-fluoropurine 
• 395075-17-9 1-O-acetyl-5-O-benzoyl-3,3-difluoro-3-deoxo-L-glyceropentofuranosid-3-ulose 

Downstream Products

• 581097-14-5 (+)-1-[(1S,4S)-5-O-benzoyl-2,3-dideoxy-3,3-difluoro-β-L-ribofuranosyl]-2-amino-6-chloropurine 
• 581097-15-6 (+)-1-[(1R,4S)-5-O-benzoyl-2,3-dideoxy-3,3-difluoro-α-L-ribofuranosyl]-2-amino-6-chloropurine 

Relevant articles and documents

l-2',3'-Didehydro-2',3'-dideoxy-3'-fluoronucleosides: synthesis, anti-HIV activity, chemical and enzymatic stability, and mechanism of resistance.

As antiviral nucleosides containing a 2',3'-unsaturated sugar moiety with 2'-fluoro substitution are endowed with increased stabilization of the glycosyl bond, it was of interest to investigate the influence of the fluorine atom at the 3'-position. Variou