58169-99-6

Basic information

• Product Name: 2,3,4,6-tetrabromo-m-cresol
• Synonyms: 2,3,4,6-tetrabromo-m-cresol;Einecs 261-151-8;Phenol, 2,3,4,6-tetrabromo-5-methyl-;Tetrabromo-m-cresol
• CAS NO: 58169-99-6
• Molecular Formula: C₇H₄Br₄O
• Molecular Weight: 424.73
• EINECS: 261-151-8
• Mol File: 58169-99-6.mol
• Article Data: 4

Chemical Properties

• Melting Point: 196 °C
• Boiling Point: 330.7°Cat760mmHg
• Flash Point: 153.8°C
• Appearance: /
• Density: 2.509g/cm³
• Vapor Pressure: 8.49E-05mmHg at 25°C
• Refractive Index: 1.678
• PKA: 5.50±0.33(Predicted)
• CAS DataBase Reference: 2,3,4,6-tetrabromo-m-cresol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4,6-tetrabromo-m-cresol(58169-99-6)
• EPA Substance Registry System: 2,3,4,6-tetrabromo-m-cresol(58169-99-6)

Safety Data

• Hazardous Substances Data: 58169-99-6(Hazardous Substances Data)

Usage

General Description

2,3,4,6-tetrabromo-m-cresol is a chemical compound that belongs to the class of brominated organic compounds. It is commonly used as a disinfectant and a biocide in various industrial and consumer products. It is effective at controlling microbial growth and is used in personal care products, plastics, and wood preservation. The compound is manufactured through chemical synthesis and exists as a white to off-white crystalline powder. It is important to handle this chemical with care and follow safety guidelines when using it due to its potential harmful effects on human health and the environment.

InChI:InChI=1/C7H4Br4O/c1-2-3(8)5(10)6(11)7(12)4(2)9/h12H,1H3

Upstream product

• 95-65-8 3,4-Dimethylphenol 
• 89-83-8 thymol 
• 4619-74-3 2,4,6-tribromo-m-cresol 
• 63113-36-0 2,5,6-tribromo-3,4-dimethylphenol 
• 34946-83-3 2,4,4,6-tetrabromo-3-methyl-cyclohexa-2,5-dienone 
• 108-39-4 3-methyl-phenol 
• 100-84-5 1-methoxy-3-methyl-benzene 
• 7726-95-6 bromine 
• 7727-15-3 aluminium bromide 
• 10458-14-7 Menthone 
• 1076-56-8 Thymol methyl ether 
• 621-32-9 3-ethoxytoluene 
• 60-29-7 diethyl ether 
• 41438-18-0 4-hydroxy-2-methyl-benzaldehyde 

Downstream Products

• 29666-53-3 3,5,6-tribromotoluquinone 
• 74204-00-5 3-bromo-5-methylphenol 
• 77339-23-2 2,4,4,5,6-pentabromo-3-methylcyclohexa-2,5-dienone 
• 108-39-4 3-methyl-phenol 
• 136386-75-9 (3-bromo-5-methyl-phenoxy)-tert-butyl-dimethyl-silane 
• 745809-48-7 3-{[(tert-butyl)(dimethyl)sily]oxy}-5-methylbenzaldehyde 
• 745809-49-8 1-[3-(tert-butyldimethylsilanyloxy)-5-methylphenyl]but-3-yn-1-ol 
• 745809-55-6 (+)-3-[2-(tert-butyldimethylsilyloxy)but-3-ynyl]-5-methylphenol 
• 745809-50-1 1-acetoxy-3-[1-(tert-butyldimethylsilanyloxy)but-3-ynyl]-5-methylbenzene 
• 745809-29-4 (+)-3-(tert-butyldimethylsilyloxy)-4-(3-acetoxy-5-methylphenyl)-1-butyne 
• 745809-57-8 1-(tert-butyldimethylsilanyloxy)-3-[1-(tert-butyldimethylsilanyloxy)but-3-ynyl]-5-methylbenzene 
• 745809-52-3 2-[2-(tert-butyldimethylsilanyloxy)-2-(3-hydroxy-5-methylphenyl)ethyl]-5,8-bis(methoxymethoxy)-[1,4]naphthoquinone 
• 745809-58-9 2-[2-(tert-butyldimethylsilanyloxy)-2-(3-acetoxy-5-methylphenyl)ethyl]-5,8-bis(methoxymethoxy)-[1,4]naphthoquinone 
• 745809-51-2 acetic acid 3-[1-(tert-butyl-dimethyl-silanyloxy)-2-(1-hydroxy-4-methoxy-5,8-bis-methoxymethoxy-naphthalen-2-yl)-ethyl]-5-methyl-phenyl ester 

Relevant articles and documents

Studies on the synthesis of landomycin A. Synthesis of the originally assigned structure of the aglycone, landomycinone, and revision of structure

The originally proposed structure (2) of landomycinone, the aglycone of landomycin A, has been synthesized and shown to be nonidentical to the naturally derived landomycin A aglycone. The synthesis of 2 features the Doetz benzannulation reaction of chromium carbene 5 and alkyne 6, and the intramolecular Michael-type cyclization reaction of the phenolic naphthoquinone 20. It is proposed that natural landomycinone possesses the alternative structure 3, but attempts to access this structure via the Michael-type cyclization of the isomeric phenolic naphthoquinone 38 have been unsuccessful.

Naturally Occurring Dibenzofurans. Part 5. Synthesis of Melacarpic Acid

The total synthesis of the lichen dibenzofuran melacarpic acid (5) was achieved by intramolecular Ullman coupling of methyl 5-bromo-4-(2-bromo-5-methoxy-3-methylphenoxy)-6-heptyl-2-methoxybenzoate (48) or methyl 6-heptyl-5-iodo-4-(2-iodo-5-methoxy-3-methyl-4-nitrophenoxy)-2-methoxybenzoate (46) followed by appropriate transformations.