58172-29-5Relevant articles and documents
Identification of Novel Macrocyclic Peptidase Substrates via On-Bead Enzymatic Cyclization
Hansen, Kristina K.,Hansen, Henrik C.,Clark, Ryan C.,Bartlett, Paul A.
, p. 8459 - 8464 (2007/10/03)
Peptidase-catalyzed formation of macrocyclic lactams on solid phase identifies ring systems that are favorably bound in the enzyme active site. We evaluated several cyclic peptide motifs linked by ester bonds between the P2 and P1′ or the P1 and P2′ side