581800-01-3

Basic information

• Product Name: 2-tert-butoxycarbonylamino-4-{1-[2-tert-butoxycarbonyl-1-(1-tert-butoxycarbonyl-2-tritylsulfanyl-ethylcarbamoyl)-ethylcarbamoyl]-2-tritylsulfanyl-ethylcarbamoyl}-butyric acid tert-butyl ester
• Synonyms: 2-tert-butoxycarbonylamino-4-{1-[2-tert-butoxycarbonyl-1-(1-tert-butoxycarbonyl-2-tritylsulfanyl-ethylcarbamoyl)-ethylcarbamoyl]-2-tritylsulfanyl-ethylcarbamoyl}-butyric acid tert-butyl ester
• CAS NO: 581800-01-3
• Molecular Weight: 1221.59
• Mol File: 581800-01-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-tert-butoxycarbonylamino-4-{1-[2-tert-butoxycarbonyl-1-(1-tert-butoxycarbonyl-2-tritylsulfanyl-ethylcarbamoyl)-ethylcarbamoyl]-2-tritylsulfanyl-ethylcarbamoyl}-butyric acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-tert-butoxycarbonylamino-4-{1-[2-tert-butoxycarbonyl-1-(1-tert-butoxycarbonyl-2-tritylsulfanyl-ethylcarbamoyl)-ethylcarbamoyl]-2-tritylsulfanyl-ethylcarbamoyl}-butyric acid tert-butyl ester(581800-01-3)
• EPA Substance Registry System: 2-tert-butoxycarbonylamino-4-{1-[2-tert-butoxycarbonyl-1-(1-tert-butoxycarbonyl-2-tritylsulfanyl-ethylcarbamoyl)-ethylcarbamoyl]-2-tritylsulfanyl-ethylcarbamoyl}-butyric acid tert-butyl ester(581800-01-3)

Safety Data

• Hazardous Substances Data: 581800-01-3(Hazardous Substances Data)

Upstream product

• 581799-99-7 N-(1-tert-butoxycarbonyl-2-tritylsulfanyl-ethyl)-3-[2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-tritylsulfanyl-propionylamino]-succinamic acid tert-butyl ester 
• 581799-97-5 N-(1-tert-butoxycarbonyl-2-tritylsulfanyl-ethyl)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-succinamic acid tert-butyl ester 
• 581799-98-6 3-amino-N-(1-tert-butoxycarbonyl-2-tritylsulfanyl-ethyl)-succinamic acid tert-butyl ester 
• 76587-61-6 S-(triphenylmethyl)-L-cysteine tert-butyl ester 
• 71989-14-5 Fmoc-(tBu)Asp-OH 
• 24277-39-2 N-tert-butoxycarbonyl glutamic acid tert-butyl ester 
• 581800-00-2 3-(2-amino-3-tritylsulfanyl-propionylamino)-N-(1-tert-butoxycarbonyl-2-tritylsulfanyl-ethyl)-succinamic acid tert-butyl ester 

Relevant articles and documents

Synthesis and biological evaluation of the disulfide form of the glutathione analogue γ-(L-glutamyl)-L-cysteinyl-L-aspartyl-L-cysteine

By using the chain to chain mode of cyclization the title glutathione analogue γ-Glu-Cys-Asp-Cys (4), containing the 11-membered disulfide ring -Cys-Asp-Cys- replacing the native -Cys-Gly fragment, has been synthesized and characterized together with its reduced dithiol form γ-Glu-Cys-Asp-Cys (5). The activity of (4) with γ-glutamyl-transferase and glutathione reductase has been evaluated and compared with those of the two conformationally restricted glutathione analogues (2) and (3) previously reported.