58265-35-3 Usage
General Description
2,2,3-trimethyl-N-phenyl-butanamide is a chemical compound with the molecular formula C14H21NO. It is a derivative of butyric acid and contains a phenyl group and three methyl groups attached to the nitrogen and carbon atoms, respectively. 2,2,3-trimethyl-N-phenyl-butanamide is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It has been found to exhibit pharmacological activities, such as antinociceptive (pain-relieving) and anti-inflammatory effects. Additionally, 2,2,3-trimethyl-N-phenyl-butanamide has been studied for its potential use in organic synthesis and as a building block for the development of new compounds with improved properties.
Check Digit Verification of cas no
The CAS Registry Mumber 58265-35-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,2,6 and 5 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 58265-35:
(7*5)+(6*8)+(5*2)+(4*6)+(3*5)+(2*3)+(1*5)=143
143 % 10 = 3
So 58265-35-3 is a valid CAS Registry Number.
InChI:InChI=1/C13H19NO/c1-10(2)13(3,4)12(15)14-11-8-6-5-7-9-11/h5-10H,1-4H3,(H,14,15)
58265-35-3Relevant articles and documents
Iron-Catalyzed Oxidative Coupling Reaction of Isocyanides and Simple Alkanes towards Amide Synthesis
Yuan, Hongdong,Liu, Zhiqiang,Shen, Yushu,Zhao, Hongbin,Li, Chunju,Jia, Xueshun,Li, Jian
supporting information, p. 2009 - 2013 (2019/03/21)
An iron-catalyzed oxidative coupling reaction of isocyanide and readily available alkane has been disclosed. In the presence of a catalytic amount of FeCp2 (10 mol%), heating a mixture of alkane, isocyanide, and DTBP in DCE allows for the formation of an amide. This reaction tolerates many simple alkanes including cycloalkanes and chain alkanes. Furthermore, a series of aromatic isocyanides having different substituents on the aromatic ring are also proven to be effective reaction components. Unfortunately, the employment of aliphatic isocyanides fails to afford the desired products. The present strategy avoids tedious procedures and the employment of toxic starting materials, thus providing an environmentally benign and efficient protocol towards amide synthesis. (Figure presented.).
