58293-86-0

Basic information

• Product Name: methyl 5-[(E)-3-methoxy-3-oxo-prop-1-enyl]furan-2-carboxylate
• Synonyms: (E)-METHYL 5-(3-METHOXY-3-OXOPROP-1-ENYL)FURAN-2-CARBOXYLATE;(E)-METHYL 5-(3-METHOXY-3-OXOPROP-1-EN-1-YL)FURAN-2-CARBOXYLATE;2-Furancarboxylic acid, 5-[(1E)-3-methoxy-3-oxo-1-propen-1-yl]-, methyl ester
• CAS NO: 58293-86-0
• Molecular Formula: C₁₀H₁₀O₅
• Molecular Weight: 210.1834
• Mol File: 58293-86-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: 73-74 °C(Solv: chloroform (67-66-3))
• Boiling Point: 329.4°C at 760 mmHg
• Flash Point: 153°C
• Density: 1.228g/cm³
• Vapor Pressure: 0.000178mmHg at 25°C
• Refractive Index: 1.527
• CAS DataBase Reference: methyl 5-[(E)-3-methoxy-3-oxo-prop-1-enyl]furan-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 5-[(E)-3-methoxy-3-oxo-prop-1-enyl]furan-2-carboxylate(58293-86-0)
• EPA Substance Registry System: methyl 5-[(E)-3-methoxy-3-oxo-prop-1-enyl]furan-2-carboxylate(58293-86-0)

Safety Data

• Hazardous Substances Data: 58293-86-0(Hazardous Substances Data)

Upstream product

• 2527-99-3 methyl 5-bromo-2-furoate 
• 292638-85-8 acrylic acid methyl ester 
• 611-13-2 2-furoic acid methyl ester 

Relevant articles and documents

A preparative route to methyl 3-(heteroaryl)acrylates using Heck methodology

Methyl 3-(heteroaryl)acrylates were prepared using Heck coupling of heteroarene halides with methyl acrylate mediated by Pd(OAc)2/ P(OCH3)3. Reactions were highly efficient (reaction times between 60 and 120 min) and scalable to 100 g of heteroarene halide. The isolated yields are from 76 to 99%.

Process for preparation of substituted olefins

The present invention relates to a process for the preparation of aromatic or furyl substituted olefins, which comprises reacting an olefinic compound with an aromatic compound or furan compound in the presence of carbon monoxide by using a rhodium carbonyl complex as a catalyst to form a corresponding aromatic or furyl substituted olefin.