583044-69-3

Basic information

• Product Name: [1,1'-Biphenyl]-4-sulfonamide, 4'-chloro-N-(2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)-
• CAS NO: 583044-69-3
• Molecular Formula: C22H21ClN2O2S
• Molecular Weight: 412.94
• Mol File: 583044-69-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [1,1'-Biphenyl]-4-sulfonamide, 4'-chloro-N-(2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: [1,1'-Biphenyl]-4-sulfonamide, 4'-chloro-N-(2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)-(583044-69-3)
• EPA Substance Registry System: [1,1'-Biphenyl]-4-sulfonamide, 4'-chloro-N-(2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)-(583044-69-3)

Safety Data

• Hazardous Substances Data: 583044-69-3(Hazardous Substances Data)

Upstream product

• 20443-74-7 4'-chlorobiphenyl-4-sulfonyl chloride 
• 118454-24-3 7-amino-1,2,4,5-tetrahydro-benzo[d]azepine-3-carboxylic acid tert-butyl ester 
• 956103-24-5 7-(4'-chloro-biphenyl-4-sulfonylamino)-1,2,4,5-tetrahydro-benzo[d]azepine-3-carboxylic acid tert-butyl ester 

Relevant articles and documents

Studies towards the identification of a new generation of atypical antipsychotic agents

A rational structure-activity relationship study around compound (1) is reported. The lead optimisation programme led to the identification of sulfonamide (25), a molecule combining dopamine D2/D3 receptor antagonism with serotonin 5