58377-44-9 Usage
Description
Tert-butyl N-methoxycarbamate, also known as N-Boc-O-methyl hydroxylamine, is an organic compound with the chemical formula C5H9NO2. It is a derivative of hydroxylamine, featuring a tert-butyl carbamate group and a methoxy group. tert-butyl N-methoxycarbamate is known for its reactivity and is commonly utilized in the synthesis of various organic molecules.
Uses
Used in Insecticide Production:
Tert-butyl N-methoxycarbamate is used as a synthetic intermediate for the preparation of (pyridinylmethylamino)furanones, which are compounds with insecticidal properties. These insecticides are employed in the agricultural industry to control pests and protect crops from damage, thereby ensuring a stable food supply and reducing economic losses due to pest infestations. The use of N-Boc-O-methyl hydroxylamine in the synthesis of these insecticides highlights its importance in the development of effective pest control strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 58377-44-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,3,7 and 7 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 58377-44:
(7*5)+(6*8)+(5*3)+(4*7)+(3*7)+(2*4)+(1*4)=159
159 % 10 = 9
So 58377-44-9 is a valid CAS Registry Number.
58377-44-9Relevant articles and documents
Asymmetric Phase-Transfer Catalytic aza-Michael Addition to Cyclic Enone: Highly Enantioselective and Diastereoselective Synthesis of Cyclic 1,3-Aminoalcohols
Lee, Jaeyong,Ban, Jeong Woo,Kim, Jeongseok,Yang, Sehun,Lee, Geumwoo,Dhorma, Lama Prema,Kim, Mi-Hyun,Ha, Min Woo,Hong, Suckchang,Park, Hyeung-Geun
supporting information, p. 1647 - 1651 (2022/03/03)
The highly enantioselective aza-Michael reaction of tert-butyl β-naphthylmethoxycarbamate to cyclic enones has been accomplished by using a new cinchona alkaloid derived C(9)-urea ammonium catalyst under phase-transfer catalysis conditions with up to 98% ee at 0 °C. The resulting aza-Michael adducts can be converted to versatile intermediates by selective deprotection and the cyclic 1,3-aminoalcohols by diastereoselective reduction with up to 32:1, which have been widely used as important pharmacophores in pharmaceutical development.
MITOTIC KINESIN INHIBITORS AND METHODS OF USE THEREOF
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Page/Page column 48-49, (2008/06/13)
This invention relates to inhibitors of mitotic kinesins, particularly KSP, and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharmaceutical compositions in the treatment of various disorders.