583873-38-5 Usage
Imidazole ring
A five-membered aromatic ring with two nitrogen atoms at positions 1 and 3, contributing to its electronic properties and potential for coordination with metal ions.
Carboxamide group
A functional group consisting of an amide group (-CONH2) attached to a carbonyl group (-CO-), which can participate in hydrogen bonding and may contribute to the compound's solubility and biological activity.
Chiral center
The compound has a chiral carbon atom (C1) with four different substituents, leading to the existence of stereoisomers (enantiomers and diastereomers) that may have different biological activities and pharmacokinetic properties.
Substituted benzoxazole
A benzoxazole ring (a fused oxazole and benzene ring) is substituted with a 4-chlorophenyl group, which may influence the compound's electronic properties, lipophilicity, and interaction with biological targets.
Siloxane functionality
A silicon-based functional group (-Si(CH3)3) is attached to a propyl chain, which may contribute to the compound's lipophilicity, stability, and potential for use in drug delivery systems.
Potential applications in medicinal chemistry
Due to its structural complexity and diverse functional groups, the compound may have potential applications in drug design and discovery, as well as in the development of new therapeutic agents.
Structural complexity
The compound's complex structure may lead to diverse biological activities and pharmacological properties, which require further research and investigation to fully understand its chemical and biological characteristics.
Check Digit Verification of cas no
The CAS Registry Mumber 583873-38-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,8,3,8,7 and 3 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 583873-38:
(8*5)+(7*8)+(6*3)+(5*8)+(4*7)+(3*3)+(2*3)+(1*8)=205
205 % 10 = 5
So 583873-38-5 is a valid CAS Registry Number.
583873-38-5Relevant articles and documents
Rational design of non-nucleoside, potent, and orally bioavailable adenosine deaminase inhibitors: Predicting enzyme conformational change and metabolism
Terasaka, Tadashi,Tsuji, Kiyoshi,Kato, Takeshi,Nakanishi, Isao,Kinoshita, Takayoshi,Kato, Yasuko,Kuno, Masako,Inoue, Takeshi,Tanaka, Kohichiro,Nakamura, Katsuya
, p. 4750 - 4753 (2007/10/03)
From metabolic considerations and prediction of an inhibitor-induced conformational change, novel adenosine deaminase (ADA) inhibitors with improved activities and oral bioavailability have been developed on the basis of our originally designed non-nucleo
