585-18-2 Usage
Description
(2,3-dihydroxy-4-oxo-butoxy)phosphonic acid, also known as D-Erythrose 4-Phosphate, is a phosphorylated conjugate of D-Erythrose, a tetrose carbohydrate. It carries a phosphate group at the 4th position and serves as an intermediate in the pentose phosphate pathway and Calvin cycle. (2,3-dihydroxy-4-oxo-butoxy)phosphonic acid has potential applications in various industries due to its unique chemical properties and role in metabolic pathways.
Uses
Used in Pharmaceutical Industry:
(2,3-dihydroxy-4-oxo-butoxy)phosphonic acid is used as a potential anticariogenic sweetener for [application reason], as it has been tested along with L-Erythrulose as a blend. Its role in the pentose phosphate pathway and Calvin cycle also makes it a promising candidate for pharmaceutical research and development.
Used in Food Industry:
In the food industry, (2,3-dihydroxy-4-oxo-butoxy)phosphonic acid is used as a potential sweetener for [application reason], due to its testing as an anticariogenic agent when combined with L-Erythrulose. This could lead to the development of healthier and more natural sweeteners for various food products.
Used in Biotechnology and Research:
(2,3-dihydroxy-4-oxo-butoxy)phosphonic acid is used as a key intermediate in the pentose phosphate pathway and Calvin cycle for [application reason], making it an essential compound for research in biotechnology and cellular metabolism. Its role in these pathways can provide insights into various biological processes and potential therapeutic targets.
Used in Chemical Synthesis:
In the field of chemical synthesis, (2,3-dihydroxy-4-oxo-butoxy)phosphonic acid is used as a building block or precursor for [application reason], the synthesis of various complex molecules and compounds. Its unique structure and functional groups make it a valuable starting material for the development of new chemicals and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 585-18-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,8 and 5 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 585-18:
(5*5)+(4*8)+(3*5)+(2*1)+(1*8)=82
82 % 10 = 2
So 585-18-2 is a valid CAS Registry Number.
InChI:InChI=1/C4H9O7P/c5-1-3(6)4(7)2-11-12(8,9)10/h1,3-4,6-7H,2H2,(H2,8,9,10)/p-2/t3-,4+/m0/s1
585-18-2Relevant articles and documents
Cloning, expression, purification, cofactor requirements, and steady state kinetics of phosphoketolase-2 from Lactobacillus plantarum
Yevenes, Alejandro,Frey, Perry A.
, p. 121 - 127 (2008)
The genes xpk1 and xpk2(Δ1-21) encoding phosphoketolase-1 and (Δ1-7)-truncated phosphoketolase-2 have been cloned from Lactobacillus plantarum and expressed in Escherichia coli. Both gene-products display phosphoketolase activity on fructose-6-phosphate in extracts. A N-terminal His-tag construct of xpk2(Δ1-21) was also expressed in E. coli and produced active His-tagged (Δ1-7)-truncated phosphoketolase-2 (hereafter phosphoketolase-2). Phosphoketolase-2 is activated by thiamine pyrophosphate (TPP) and the divalent metal ions Mg2+, Mn2+, or Ca2+. Kinetic analysis and data from the literature indicate the activators are MgTPP, MnTPP, or CaTPP, and these species activate by an ordered equilibrium binding pathway, with Me2+TPP binding first and then fructose-6-phosphate. Phosphoketolase-2 accepts either fructose-6-phosphate or xylulose-5-phosphate as substrates, together with inorganic phosphate, to produce acetyl phosphate and either erythrose-4-phosphate or glyceraldehyde-3-phosphate, respectively. Steady state kinetic analysis of acetyl phosphate formation with either substrate indicates a ping pong kinetic mechanism. Product inhibition patterns with erythrose-4-phosphate indicate that an intermediate in the ping pong mechanism is formed irreversibly. Background mechanistic information indicates that this intermediate is 2-acetyl-TPP. The irreversibility of 2-acetyl-TPP formation might explain the overall irreversibility of the reaction of phosphoketolase-2.
