58550-34-8

Basic information

• Product Name: 2-Propenal, 2-methyl-3-(4-nitrophenyl)-, (E)-
• CAS NO: 58550-34-8
• Molecular Formula: C10H9NO3
• Molecular Weight: 191.186
• Mol File: 58550-34-8.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: 2-Propenal, 2-methyl-3-(4-nitrophenyl)-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenal, 2-methyl-3-(4-nitrophenyl)-, (E)-(58550-34-8)
• EPA Substance Registry System: 2-Propenal, 2-methyl-3-(4-nitrophenyl)-, (E)-(58550-34-8)

Safety Data

• Hazardous Substances Data: 58550-34-8(Hazardous Substances Data)

Usage

Physical State

Yellow to orange solid

Common Uses

Pesticide
Manufacturing of pharmaceuticals

Chemical Classification

Aldehyde

Functional Groups

Contains a nitrophenyl group

Color

Distinctive yellow to orange due to the nitrophenyl group

Odor

Strong odor

Toxicity

Considered toxic to aquatic organisms

Potential Applications

Medicinal chemistry
Development of new drugs

Versatility

Exhibits various uses and potential benefits in different fields.

Upstream product

• 555-16-8 4-nitrobenzaldehdye 
• 123-38-6 propionaldehyde 
• 53618-29-4 (E)-ethyl 2-methyl-3-(4-nitrophenyl)acrylate 
• 24720-64-7 2-(triphenylphosphoranylidene)propionaldehyde 
• 37542-81-7 (2E)-2-methyl-3-(4-nitrophenyl)prop-2-en-1-ol 
• 15174-47-7 α-methyl-trans-cinnamaldehyde 
• 154581-92-7 (Z)-2-Trimethylsilanyl-1-trimethylsilanyloxy-propene 

Downstream Products

• 52338-39-3 3t-(4-amino-phenyl)-2-methyl-acrylaldehyde 
• 55191-23-6 5-methyl-6t-(4-nitro-phenyl)-hexa-3t,5-dien-2-one 
• 139212-73-0 (R,S) 1-hydroxy-1-(4-methoxy-6-methyl-2H-pyran-2-on-3-yl)-2-methyl-3-(4-nitrophenyl)-2-propene 
• 444760-02-5 1-((1E,3Z)-4-iodo-2-methyl-penta-1,3-dienyl)-4-nitrobenzene 
• 1343490-49-2 2-((1E,5E)-4-hydroxy-5-methyl-6-(4-nitrophenyl)hexa-1,5-dienyl)-6-methoxy-3,5-dimethyl-4H-pyran-4-one 
• 37542-81-7 (2E)-2-methyl-3-(4-nitrophenyl)prop-2-en-1-ol 
• 1374412-65-3 4-methyl-3-(4-nitrophenyl)pent-4-en-1-ol 
• 22388-90-5 (2E,4E)-2,4-dimethyl-5-(4-nitrophenyl)penta-2,4-dienoic acid 

Relevant articles and documents

Regioselective functionalization of pyrones: Facile synthesis of 6-styrylpyrones via KHMDS-mediated aldol condensation

Herein, we disclose our efforts directed toward the synthesis of the kavalactone-based natural product penstyrylpyrone and other related 4-OMe-2-pyrones possessing diverse substituents at the 3-, 5-, and 7-positions. Further, a facile approach to access 6-styrylpyrones via the KHMDS-mediated regioselective aldol condensation of 2-pyrones is described with moderate substrate scope and good to high yields (58–80%). The utility of this methodology was exemplified by the stereoselective construction of desmethoxyyangonin, asnipyrone A, and asnipyrone B.

Synthesis of conjugated multiunsaturated thioesters via one-pot TiCl4-promoted aldol condensation

TiCl4-promoted aldol condensations of S-4-chlorophenyl thioesters with enals or dienals led to the production of dienyl or trienyl thioesters in good yields. Due to good crystallinity, products with high E/Z ratios were obtained by simple filtr

Multifactorial control of iteration events in a modular polyketide assembly line

Freedom and control: First insights into the rare programmed iteration of an individual polyketide synthase (PKS) module were obtained from the analysis and mutation of aureothin (1) synthase. The first ketosynthase (KS) domain primes the PKS, allowing intermediate retrotransfer. Addition of a designated loading module results in a complete loss of iteration. The downstream KS functions as a gatekeeper for correct chain length. Copyright