58577-62-1Relevant articles and documents
Screening on the use of Kluyveromyces marxianus CBS 6556 growing cells as enantioselective biocatalysts for ketone reductions
Vitale, Paola,Perna, Filippo Maria,Perrone, Maria Grazia,Scilimati, Antonio
, p. 1985 - 1993 (2012/03/22)
The versatility of Kluyveromyces marxianus CBS 6556 growing cells in the enantioselective reduction of ketone functionalities to the corresponding alcohols was exploited. In particular, methyl ketones were reduced to (S)-alcohols with ees of up to 96%. Longer chain alkyl ketones afforded, under the same experimental condition, (R)-alcohols with an ee of up to 84%. Interestingly, carbon-carbon double and the triple bonds can also be reduced in the presence of Kluyveromyces marxianus CBS 6556 yeast. A cyclic ketone, such as 2-tetralone, was also quantitatively reduced to its corresponding (S)-alcohol with ee = 76%.
SYNTHESIS OF (2S,3R,7RS)-STEGOBINONE (2,3-DIHYDRO-2,3,5-TRIMETHYL-6-(1-METHYL-2-OXOBUTYL)-4H-PYRAN-4-ONE) AND ITS (2R,3S,7RS)-ISOMER. THE PHEROMONE OF THE DRUGSTORE BEETLE
Mori, K.,Ebata, T.,Sakakibara, M.
, p. 709 - 713 (2007/10/02)
Reaction of acetaldehyde with the trianion of 4,6-dimethylnonane-3,5,7-trione followed by acidification yielded a stereoisomeric mixture of stegobinone, the pheromone of Stegobium paniceum L.Acylation of the dianion derived from 4-methylheptane-3,5-dione
