58584-61-5

Basic information

• Product Name: 2-Amino-6-chloro-3-pyridinecarboxaldehyde
• Synonyms: 2-Amino-6-chloro-3-pyridinecarboxaldehyde;2-aMino-6-chloronicotinaldehyde;3-Pyridinecarboxaldehyde, 2-aMino-6-chloro-;2-AMino-6-chloro-pyridine-3-carbaldehyde
• CAS NO: 58584-61-5
• Molecular Formula: C₆H₅ClN₂O
• Molecular Weight: 156.57
• Mol File: 58584-61-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Density: 1.442
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 2-Amino-6-chloro-3-pyridinecarboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-6-chloro-3-pyridinecarboxaldehyde(58584-61-5)
• EPA Substance Registry System: 2-Amino-6-chloro-3-pyridinecarboxaldehyde(58584-61-5)

Safety Data

• Hazardous Substances Data: 58584-61-5(Hazardous Substances Data)

Usage

Uses

2-Amino-6-chloronicotinaldehyde is a useful synthetic compound.

Upstream product

• 873936-99-3 2-amino-6-chloro-N-methoxy-N-methylnicotinamide 
• 936344-72-8 ethyl 2-amino-6-chloronicotinate 
• 58584-60-4 (2-amino-6-chloro-pyridin-3-yl)-methanol 
• 58584-92-2 2-amino-6-chloronicotinic acid 
• 38496-18-3 2,6-dichloropyridine-3-carboxylic acid 
• 294659-72-6 tert-butyl N-(6-chloro-3-formyl-2-pyridyl)carbamate 
• 45644-21-1 6-chloropyridin-2-amine 
• 159603-71-1 t-butyl N-(6-chloro-2-pyridinyl)carbamate 

Relevant articles and documents

1,8-NAPHTHYRIDINONE COMPOUNDS AND USES THEREOF

1,8-naphthyridinone compounds as modulators of an adenosine receptor are provided. The compounds may find use as therapeutic agents for the treatment of diseases mediated through a G-protein-coupled receptor signaling pathway and may find particular use in oncology.

CHEMICAL COMPOUNDS AS H-PGDS INHIBITORS

A compound of formula (I) wherein R1, R2, R3, R4, X, Y, and A are as defined herein. The compounds of the present invention are inhibitors of hematopoietic prostaglandin D synthase (H-PGDS) and can be useful in the treatment of Duchenne muscular dystrophy. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting H-PGDS activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.

1,6- AND 1,8-NAPHTHYRIDINES

Compounds of formula and pharmaceutically acceptable salts thereof are described, as well as the pharmaceutical compositions containing said compounds and their pharmaceutically acceptable salts, and the use of said compounds and pharmaceutical compositions for the treatment, control or amelioration of proliferative diseases, including cancer, Down syndrome or early onset Alzheimer's disease.