5860-71-9

Basic information

• Product Name: 2,6-DIMETHYL-NICOTINIC ACID
• Synonyms: 2,6-DIMETHYL-NICOTINIC ACID;3-Pyridinecarboxylicacid,2,6-dimethyl-(9CI);3-Pyridinecarboxylic acid, 2,6-dimethyl;2,6-dimethyl-3-pyridinecarboxylic acid;2,6-lutidine-3-carboxylic acid;2,6-Dimethylpyridine-3-carboxylic acid, 3-Carboxy-2,6-dimethylpyridine
• CAS NO: 5860-71-9
• Molecular Formula: C₈H₉NO₂
• Molecular Weight: 151.16
• Product Categories: CARBOXYLICACID;Carboxylic Acids;Pyridines;Carboxylic Acids;Building Blocks;Pyridine
• Mol File: 5860-71-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: 151 °C
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.417 g/cm³
• Refractive Index: 1.651
• PKA: 2.18±0.25(Predicted)
• CAS DataBase Reference: 2,6-DIMETHYL-NICOTINIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-DIMETHYL-NICOTINIC ACID(5860-71-9)
• EPA Substance Registry System: 2,6-DIMETHYL-NICOTINIC ACID(5860-71-9)

Safety Data

• Hazardous Substances Data: 5860-71-9(Hazardous Substances Data)

Usage

Uses

2,6-Dimethylnicotinic acid

InChI:InChI=1/C13H11N3O4S/c17-12(9-3-5-10(6-4-9)16(18)19)15-13(21)14-8-11-2-1-7-20-11/h1-7H,8H2,(H2,14,15,17,21)

Upstream product

• 1721-13-7 ethyl 2,6-dimethylnicotinate 
• 1122-43-6 2,6-dimethyl-3-hydroxypyridine 
• 124-38-9 carbon dioxide 

Downstream Products

• 108619-14-3 2-methyl-6-(3-nitro-trans-styryl)-nicotinic acid 
• 113056-89-6 2,6-bis-(3-nitro-trans-styryl)-nicotinic acid 
• 136819-91-5 2-Methyl-6-styryl-3-nicotinic acid 
• 108-48-5 2,6-dimethylpyridine 
• 1204535-76-1 (2S)-1-[(2,6-Dimethyl-3-pyridinyl)carbonyl]-2-methyl-4-{[4-(trifluoromethyl)phenyl]sulfonyl}piperazine 
• 1600565-92-1 (2,4-dichloro-3-phenylquinolin-6-yl)(2,6-dimethylpyridin-3-yl)(1-methyl-1H-imidazol-5-yl)methanol 
• 15513-52-7 3-nitro-2,6-lutidine 
• 127067-18-9 methyl 2,6-dimethylnicotinate 
• 33259-21-1 2,6-dimethyl-4-hydroxypyridine-3-carboxylic acid 

Relevant articles and documents

Nickel-catalyzed carboxylation of aryl and heteroaryl fluorosulfates using carbon dioxide

The development of efficient and practical methods to construct carboxylic acids using CO2 as a C1 synthon is of great importance. Nickel-catalyzed carboxylation of aryl fluorosulfates and heteroaryl fluorosulfates with CO2 is described, affording arene carboxylic acids with good to excellent yields under mild conditions. In addition, a one-pot phenol fluorosulfation/carboxylation is developed.