58605-12-2

Basic information

• Product Name: METHYL 2,4-DINITROPHENYLACETATE
• Synonyms: 2,4-dinitrophenylaceticacidmethylester;METHYL 2,4-DINITROPHENYLACETATE;Benzeneacetic acid, 2,4-dinitro-, methyl ester;Methyl 2-(2,4-dinitrophenyl)acetate;2-(2,4-dinitrophenyl)acetic acid methyl ester;methyl 2-(2,4-dinitrophenyl)ethanoate
• CAS NO: 58605-12-2
• Molecular Formula: C₉H₈N₂O₆
• Molecular Weight: 240.17
• Mol File: 58605-12-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 362°Cat760mmHg
• Flash Point: 168.5°C
• Appearance: /
• Density: 1.447g/cm³
• Vapor Pressure: 1.99E-05mmHg at 25°C
• Refractive Index: 1.581
• CAS DataBase Reference: METHYL 2,4-DINITROPHENYLACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 2,4-DINITROPHENYLACETATE(58605-12-2)
• EPA Substance Registry System: METHYL 2,4-DINITROPHENYLACETATE(58605-12-2)

Safety Data

• Hazardous Substances Data: 58605-12-2(Hazardous Substances Data)

Usage

General Description

Methyl 2,4-dinitrophenylacetate is a chemical compound usually recognized with the molecular formula of C9H7N2O7, and a weight of 253.16 g/mol. It's characterized by an acetate ester group and nitro group substituents attached to the benzene ring. METHYL 2,4-DINITROPHENYLACETATE is commonly used in chemical synthesis. The presence of nitro groups makes it a potentially explosive material and it should be handled with care. More importantly, because it's a member of the nitrophenyl compounds, it's also relevant in biochemistry for enzyme research.

InChI:InChI=1/C9H8N2O6/c1-17-9(12)4-6-2-3-7(10(13)14)5-8(6)11(15)16/h2-3,5H,4H2,1H3

Upstream product

• 67-56-1 methanol 
• 643-43-6 (2,4-dinitro-phenyl)-acetic acid 
• 99-65-0 meta-dinitrobenzene 
• 5199-50-8 methyl 2-iodoacetate 
• 96-32-2 bromoacetic acid methyl ester 
• 103-82-2 phenylacetic acid 

Downstream Products

• 5833-19-2 bis-(2,4-dinitro-phenyl)-acetic acid methyl ester 
• 39835-14-8 2-hydroxy-4-nitro-benzonitrile 
• 5453-86-1 methyl 6-nitro-1,2-benzisoxazole-3-carboxylate 
• 643081-99-6 (2,4-diamino-phenyl)-acetic acid methyl ester 
• 22074-09-5 3-(2,4-dinitro-phenyl)-coumarin 
• 412306-92-4 2-{[(2,4-dinitro-phenyl)-methoxycarbonyl-methylene]-hydrazino}-benzoic acid 
• 349419-18-7 2-(2,4-dinitro-phenyl)-N-phenyl-acetamide 
• 6524-15-8 α-(Diphenyl-cyclopropenyliden)-2,4-dinitro-phenylessigsaeure-methylester 
• 186641-18-9 6-nitro-N-(1-benzyl-4-piperidinyl)-1,2-benzisoxazole-3-carboxamide 
• 125112-61-0 2-quinolyl-(2-nitroso-4-nitrophenyl)carbomethoxymethyl carbinol 
• 125112-64-3 5-nitro-2-pyridyl-(2-nitroso-4-nitrophenyl)carbomethoxycarbinol 

Relevant articles and documents

Supramolecular kinetic effects by pillararenes: The synergism between spatiotemporal and preorganization concepts in decarboxylation reactions

A study about spontaneous decarboxylation reactions of 3-carboxy-1,2-benzisoxazole (CBI) nitrated derivatives (6-NitroCBI and 5,6-DinitroCBI) compared with supramolecular kinetic effects promoted by two cationic pillararenes (P5A and P6A) has been carried

Substituted alkylamine derivatives and methods of use

Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Synthesis of 2-(2,6-dinitrophenyl)malonates, -acetates and acetonitrile by copper-mediated vicarious nucleophilic substitution

A regioselective, vicarious nucleophilic substitution of 1,3- dinitrobenzene with α-bromo- and iodocarbanions proceeds in the presence of copper(1) tert-butoxide and pyridine giving 2,6-dinitrophenylmalonates, 2,6- dinitrophenylacetates or 2,6-dinitrophenylacetonitrile as the only isomers from bromomalonate esters, bromoacetate esters, iodoacetate esters or iodoacetonitrile, respectively. Without copper(I) tert-butoxide, the 4- substituted isomer is the only product. We believe that the reaction proceeds via a σ-adduct of 1,3-dinitrobenzene and halocarbanion from which hydrogen and halogen are eliminated. This elimination is dependent upon the concentration of copper(I) tert-butoxide.