58607-04-8

Basic information

• Product Name: 3-(1-hydroxy-cyclohexyl)-1,1-diphenyl-prop-2-yn-1-ol
• Synonyms: 3-(1-hydroxy-cyclohexyl)-1,1-diphenyl-prop-2-yn-1-ol
• CAS NO: 58607-04-8
• Molecular Weight: 306.404
• Mol File: 58607-04-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(1-hydroxy-cyclohexyl)-1,1-diphenyl-prop-2-yn-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(1-hydroxy-cyclohexyl)-1,1-diphenyl-prop-2-yn-1-ol(58607-04-8)
• EPA Substance Registry System: 3-(1-hydroxy-cyclohexyl)-1,1-diphenyl-prop-2-yn-1-ol(58607-04-8)

Safety Data

• Hazardous Substances Data: 58607-04-8(Hazardous Substances Data)

Upstream product

• 4301-15-9 ethynyldimagnesium dibromide 
• 119-61-9 benzophenone 
• 108-94-1 cyclohexanone 
• 3923-52-2 1,1-diphenyl-2-propyn-1-ol 
• 78-27-3 1-Ethynylcyclohexan-1-ol 

Downstream Products

• 58607-49-1 1-(3-hydroxy-3,3-diphenylpropyl)cyclohexanol 

Relevant articles and documents

Catalytic Enantioselective α-Ketol Rearrangement

A highly enantioselective α-ketol rearrangement has been developed. In the presence of a chiral Cu-bisoxazoline complex, achiral β-hydroxy-α-dicarbonyls were isomerized to chiral α-hydroxy-β-dicarbonyls and their bicyclic derivatives in excellent yields and enantioselectivities. Enantioenriched 2-acyl-2-hydroxy cyclohexan-1-ones, dihydroxyhexahydrobenzofuranones, and dihydroxyhexahydro-cycloheptafuranones, with up to three stereocenters, were readily prepared from achiral starting materials in one operation. The reaction is applicable to the desymmetrization of meso substrates and kinetic resolution of racemic alcohols.