58630-07-2

Basic information

• Product Name: 5-(benzyloxy)-1-methyl-1H-indole-3-carbaldehyde
• Synonyms: 5-(benzyloxy)-1-methyl-1H-indole-3-carbaldehyde
• CAS NO: 58630-07-2
• Molecular Weight: 265.312
• Mol File: 58630-07-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 5-(benzyloxy)-1-methyl-1H-indole-3-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(benzyloxy)-1-methyl-1H-indole-3-carbaldehyde(58630-07-2)
• EPA Substance Registry System: 5-(benzyloxy)-1-methyl-1H-indole-3-carbaldehyde(58630-07-2)

Safety Data

• Hazardous Substances Data: 58630-07-2(Hazardous Substances Data)

Upstream product

• 6953-22-6 5-benzyloxyindole-3-carboxaldehyde 
• 74-88-4 methyl iodide 
• 50-00-0 formaldehyd 
• 2439-68-1 5-benzyloxy-1-methylindole 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 742105-16-4 ethyl 3-(5-benzyloxy-1-methylindol-3-yl)acrylate 
• 1292285-84-7 C₁₈H₁₆N₂O₃ 
• 2521-11-1 2-(5-benzyloxy-1-methyl-indol-3-yl)-ethylamine 
• 1292285-86-9 C₂₁H₂₄N₂O₃ 
• 1292285-85-8 C₁₈H₁₈N₂O₃ 
• 294863-07-3 1-{(R)-1-(tert-butyldimethylsilyloxy)-4-[5-(3-(4-chlorophenyl)propoxy)-1-methylindol-3-yl]-2-butyl}imidazole-4-carboxamide 
• 294863-06-2 1-[(R)-1-(tert-butyldimethylsilyloxy)-4-(1-methyl-5(3-phenylpropoxy)indol-3-yl)-2-butyl]imidazole-4-carboxamide 
• 294862-78-5 1-[(R)-4-(5-benzyloxy-1-methylindol-3-yl)-1-(tert-butyldimethylsilyloxy)-2-butyl]imidazole-4-carboxamide 
• 294863-20-0 (S)-4-(5-benzyloxy-1-methylindol-3-yl)-1-(tert-butyldimethylsilyloxy)butan-2-ol 
• 294863-19-7 (S)-4-(5-benzyloxy-1-methylindol-3-yl)butane-1,2-diol 
• 294863-16-4 ethyl 3-(5-benzyloxy-1-methylindol-3-yl)propionate 
• 294863-18-6 5-benzyloxy-3-(3-butenyl)-1-methylindole 
• 294863-17-5 3-(5-benzyloxy-1-methylindol-3-yl)propionaldehyde 

Relevant articles and documents

Electrochemically Enabled C3-Formylation and -Acylation of Indoles with Aldehydes

Reported herein is an effective strategy for oxidative cross-coupling of indoles with various aldehydes. The strategy is based on a two-step transformation via a well-known Mannich-type reaction and a C-N bond cleavage for carbonyl introduction. The key step - the C-N bond cleavage of the Mannich product - was enabled by electrochemistry. This strategy (with over 40 examples) ensures excellent functional-group tolerance as well as late-stage functionalization of pharmaceutical molecules.

THERAPEUTIC AGENTS I

Compounds of formula(I), processes for preparing such compounds, their use in the treatment of obesity, psychiatric disorders, cognitive disorders, memory disorders, schizophrenia, epilepsy, and related conditions, and neurological disorders such as dementia, multiple sclerosis, Parkinson's disease, Huntington's chorea and Alzheimer's disease and pain related disorders, and pharmaceutical compositions containing them.