58634-53-0

Basic information

• Product Name: 4,6-bis[(benzyloxy)amino]-5,6-dihydropyrimidin-2(1H)-one
• CAS NO: 58634-53-0
• Molecular Formula: C₁₈H₂₀N₄O₃
• Molecular Weight: 340.3764
• Mol File: 58634-53-0.mol
• Article Data: 0

Chemical Properties

• Density: 1.28g/cm³
• Refractive Index: 1.622
• CAS DataBase Reference: 4,6-bis[(benzyloxy)amino]-5,6-dihydropyrimidin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-bis[(benzyloxy)amino]-5,6-dihydropyrimidin-2(1H)-one(58634-53-0)
• EPA Substance Registry System: 4,6-bis[(benzyloxy)amino]-5,6-dihydropyrimidin-2(1H)-one(58634-53-0)

Safety Data

• Hazardous Substances Data: 58634-53-0(Hazardous Substances Data)

Usage

General Description

4,6-bis[(benzyloxy)amino]-5,6-dihydropyrimidin-2(1H)-one, also known as Compound JNJ 7777120, is a chemical compound that belongs to the class of dihydropyrimidines. It is a potent and selective antagonist of the histamine H4 receptor, which is involved in the regulation of inflammation and immune responses. 4,6-bis[(benzyloxy)amino]-5,6-dihydropyrimidin-2(1H)-one has been studied for its potential therapeutic use in the treatment of inflammatory and allergic diseases. Its unique chemical structure and binding properties make it a promising candidate for the development of new drugs targeting the histamine H4 receptor. However, further research is needed to fully understand its pharmacological mechanisms and potential clinical applications.

Downstream Products

• 622-33-3 N-benzyloxyamine 
• 58634-64-3 1H-pyrimidine-2,4-dione 4-(O-benzyl-oxime)