58645-50-4

Basic information

• Product Name: 1-(2-METHOXYPHENYL)-2-NITROPROPENE
• Synonyms: 2'-METHOXY-BETA-METHYL-BETA-NITROSTYRENE;1-(2-METHOXYPHENYL)-2-NITROPROPENE;1-METHOXY-2-(2-NITROPROP-1-ENYL)BENZENE
• CAS NO: 58645-50-4
• Molecular Formula: C₁₀H₁₁NO₃
• Molecular Weight: 193.2
• Product Categories: Ethanes/ethenes
• Mol File: 58645-50-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 306.136°C at 760 mmHg
• Flash Point: 136.865°C
• Appearance: /
• Density: 1.157g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.569
• CAS DataBase Reference: 1-(2-METHOXYPHENYL)-2-NITROPROPENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-METHOXYPHENYL)-2-NITROPROPENE(58645-50-4)
• EPA Substance Registry System: 1-(2-METHOXYPHENYL)-2-NITROPROPENE(58645-50-4)

Safety Data

• Hazardous Substances Data: 58645-50-4(Hazardous Substances Data)

Usage

General Description

1-(2-Methoxyphenyl)-2-nitropropene, also known as Empathy, is a chemical compound with the molecular formula C10H11NO3. It is a yellow-colored oil that is insoluble in water and soluble in organic solvents. 1-(2-METHOXYPHENYL)-2-NITROPROPENE is commonly used in the synthesis of various pharmaceuticals and organic compounds. It is also known for its potential use as a precursor in the illicit production of controlled substances. 1-(2-Methoxyphenyl)-2-nitropropene has a molecular weight of 193.2 g/mol and is classified as a substituted nitroalkene. Its chemical structure consists of a nitro group attached to a propene chain and a methoxyphenyl group, and it is important to handle it with caution due to its potential hazards if mishandled.

InChI:InChI=1/C10H11NO3/c1-8(11(12)13)7-9-5-3-4-6-10(9)14-2/h3-7H,1-2H3/b8-7+

Upstream product

• 100137-54-0 1-acetoxy-1-(2-methoxy-phenyl)-2-nitro-propane 
• 79-24-3 Nitroethane 
• 135-02-4 ortho-anisaldehyde 

Downstream Products

• 5211-62-1 1-(2-methoxyphenyl)propan-2-one 
• 116272-93-6 (2S,3R)-3-(2-Methoxy-phenyl)-4-methyl-1-oxy-2-phenyl-2,3-dihydro-azete-2-carboxylic acid diethylamide 
• 34322-76-4 1-(2'-methoxyphenyl)-2-nitropropane 
• 865376-68-7 2,5-dimethyl-4-(2-methoxyphenyl)furan-3-carboxylic acid ethyl ester 
• 93-30-1 methoxyphenamine 
• 101104-91-0 furfuryl-[2-(2-methoxy-phenyl)-1-methyl-ethyl]-amine 
• 109475-04-9 [2-(2-methoxy-phenyl)-1-methyl-ethyl]-[2]thienylmethyl-amine 
• 47302-54-5 bis-[2-(2-methoxy-phenyl)-1-methyl-ethyl]-amine 
• 93-30-1 (+)-[2-(2-methoxy-phenyl)-1-methyl-ethyl]-methyl-amine 
• 93-30-1 (-)-[2-(2-methoxy-phenyl)-1-methyl-ethyl]-methyl-amine 
• 1426079-96-0 2-(2-methoxyphenyl)-3-methylimidazo[1,2-a]pyridine 
• 1071023-32-9 (E)-N-(1-(2-methoxyphenyl)prop-1-en-2-yl)acetamide 

Relevant articles and documents

Design of phosphorus ligands with deep chiral pockets: Practical Synthesis of chiral β-arylamines by asymmetric hydrogenation

WingPhos, a C2-symmetric bisphosphorus ligand with a deep and well-defined chiral pocket was developed. It has shown high efficiency in the rhodium-catalyzed asymmetric hydrogenation of (E)-β-aryl-N-acetyl enamides, cyclic β-aryl enamides, and heterocyclic β-aryl enamides. A series of chiral β-arylisopropylamines, 2-aminotetralines, and 3-aminochromans can be synthesized with excellent ee values (nbd=3,5-norbornadiene; TON=turnover number). Copyright

Asymmetric reduction of nitroalkenes with baker's yeast

Various α,β-disubstituted and trisubstituted nitroalkenes were chemoselectively reduced with baker's yeast to the corresponding nitroalkanes. Stereoselectivities of the reduction of α,β-disubstituted nitroalkenes were modest to low, and e.e.s up to 52% were obtained. Trisubstituted nitroalkenes could be reduced to the corresponding nitroalkanes with excellent enantioselectivities, moderate diastereoselectivities and in good yield.