587-26-8 Usage
Flammability and Explosibility
Notclassified
Clinical Use
#N/A
Drug interactions
Potentially hazardous interactions with other drugs
Antibacterials: possibly reduces absorption of
quinolones - give at least 2 hours before or 4 hours
after lanthanum.
Antifungals: absorption of ketoconazole reduced -
give at least 2 hours apart.
Antimalarials: absorption of chloroquine and
hydroxychloroquine possibly reduced - give at least
2 hours apart.
Thyroid hormones: reduces absorption of
levothyroxine - give at least 2 hours apart
Metabolism
Lanthanum carbonate is poorly absorbed from the
gastrointestinal tract, with an absolute oral bioavailability
of less than 1%. The small fraction that is absorbed is
more than 99% bound to plasma proteins and is widely
distributed in the tissues, particularly the bones, the
liver, and the gastrointestinal tract. Lanthanum is not
metabolised.
It is excreted mainly in the faeces with only around
0.000031% of an oral dose excreted via the urine in
healthy subjects (renal clearance approximately 1 mL/
min, representing <2% of total plasma clearance)
Check Digit Verification of cas no
The CAS Registry Mumber 587-26-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,8 and 7 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 587-26:
(5*5)+(4*8)+(3*7)+(2*2)+(1*6)=88
88 % 10 = 8
So 587-26-8 is a valid CAS Registry Number.
InChI:InChI=1/CH2O3.La/c2-1(3)4;/h(H2,2,3,4);/q;+3/p-2