58705-82-1

Basic information

• Product Name: 2-(4-bromophenyl)-3,4-pentadien-2-ol
• Synonyms: 2-(4-bromophenyl)-3,4-pentadien-2-ol
• CAS NO: 58705-82-1
• Molecular Weight: 239.112
• Mol File: 58705-82-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-(4-bromophenyl)-3,4-pentadien-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-bromophenyl)-3,4-pentadien-2-ol(58705-82-1)
• EPA Substance Registry System: 2-(4-bromophenyl)-3,4-pentadien-2-ol(58705-82-1)

Safety Data

• Hazardous Substances Data: 58705-82-1(Hazardous Substances Data)

Upstream product

• 99-90-1 para-bromoacetophenone 
• 659-86-9 propargyl iodide 
• 50-00-0 formaldehyd 
• 115919-18-1 2-(4-bromophenyl)but-3-yn-2-ol 
• 57186-58-0 2-allenyl-5,5-dimethyl-1,3,2-dioxaborinane 

Relevant articles and documents

Coordination-Induced Stereocontrol over Carbocations: Asymmetric Reductive Deoxygenation of Racemic Tertiary Alcohols

The inherent difficulty in eliciting facial control over carbocations has limited their utility as intermediates in asymmetric catalysis. We have now shown that a docking strategy involving the reversible coordination of a substrate to a chiral transition-metal catalyst can be used to enable highly stereoselective nucleophilic attack on intermediate tertiary carbocations. This approach has been implemented to achieve the first example of enantioselective reductive deoxygenation of tertiary alcohols. This reduction occurs with high enantio- (up to 96% ee) and regioselectivity (up to >50:1 rr) by applying a novel Hantzsch ester analogue as a convenient hydride source. In-depth mechanistic studies support the involvement of a tertiary carbocation that is coordinated to the iridium metal center via the key allene moiety.

Zinc Amide Catalyzed Regioselective Allenylation and Propargylation of Ketones with Allenyl Boronate

Zinc amide catalyzed, regioselective allenylation and propargylation of ketones with allenyl boronate is reported. Tertiary allenyl and homopropargyl alcohols were obtained, respectively, in high selectivities, from the same starting materials, simply by changing the reaction conditions. The substrate scope was wide. Mechanistic studies suggest that the reactions are controlled under kinetic and thermodynamic conditions.

Anti-inflammatory 1-phenyl-2,3-butadien-1-ols, methods of use and compositions containing same

Disclosed are compounds of the class 1-phenyl-2,3-butadien-1-ol e.g. 2-(p-biphenyl)-3,4-pentadien-2-ol, which are useful by reason of their pharmacological activity in animals, e.g., as anti-inflammatory agents and tranquilizers. Said compounds can be pre