58722-34-2

Basic information

• Product Name: 1-[4-(PIPERIDINE-1-SULFONYL)-PHENYL]-ETHANONE
• Synonyms: 1-[4-(PIPERIDINE-1-SULFONYL)-PHENYL]-ETHANONE;AKOS BBS-00001195;4-PIPERIDINESULFAMYLACETOPHENONE;4-PIPRIDINSULFAMYLACETOPHENONE;1-(4-piperidin-1-ylsulfonylphenyl)ethanone
• CAS NO: 58722-34-2
• Molecular Formula: C₁₃H₁₇NO₃S
• Molecular Weight: 267.34
• Mol File: 58722-34-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 428.9°Cat760mmHg
• Flash Point: 213.2°C
• Appearance: /
• Density: 1.235g/cm³
• Vapor Pressure: 1.47E-07mmHg at 25°C
• Refractive Index: 1.559
• CAS DataBase Reference: 1-[4-(PIPERIDINE-1-SULFONYL)-PHENYL]-ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[4-(PIPERIDINE-1-SULFONYL)-PHENYL]-ETHANONE(58722-34-2)
• EPA Substance Registry System: 1-[4-(PIPERIDINE-1-SULFONYL)-PHENYL]-ETHANONE(58722-34-2)

Safety Data

• Hazardous Substances Data: 58722-34-2(Hazardous Substances Data)

Usage

General Description

1-[4-(piperidine-1-sulfonyl)-phenyl]-ethanone is a chemical compound with a molecular formula C15H20N2O3S. It is an organic compound that belongs to the class of acetophenone, which is a type of aromatic ketone. The compound contains a piperidine ring and a sulfonyl group attached to a phenyl ring. It is used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. 1-[4-(PIPERIDINE-1-SULFONYL)-PHENYL]-ETHANONE may have potential applications in medicinal chemistry, particularly in the development of new drugs for the treatment of various diseases.

InChI:InChI=1/C13H17NO3S/c1-11(15)12-5-7-13(8-6-12)18(16,17)14-9-3-2-4-10-14/h5-8H,2-4,9-10H2,1H3

Upstream product

• 110-89-4 piperidine 
• 1788-10-9 4-Acetylbenzenesulfonyl chloride 

Downstream Products

• 58722-39-7 1-(4-bromoacetyl-benzenesulfonyl)-piperidine 
• 110820-41-2 1-[4-(piperidine-1-sulfonyl)phenyl]ethanone thiosemicarbazone 
• 845674-27-3 1-[4-(piperidine-1-sulfonyl)phenyl]ethanone phenylthiosemicarbazone 
• 845674-17-1 2-({1-[4-(piperidine-1-sulfonyl)phenyl]ethylidene}hydrazono)thiazolidin-4-one 
• 845674-23-9 3-amino-2-({1-[4-(piperidine-1-sulfonyl)phenyl]ethylidene}hydrazono)thiazolidin-4-one 
• 845674-28-4 3-phenyl-2-({1-[4-(piperidine-1-sulfonyl)phenyl]ethylidene}hydrazono)thiazolidin-4-one 
• 845674-18-2 [4-oxo-2-({1-[4-(piperidine-1-sulfonyl)phenyl]ethylidene}hydrazono)thiazolidin-3-yl] acetic acid ethyl ester 
• 845674-19-3 5-[1-(4-Methoxy-phenyl)-meth-(E)-ylidene]-2-{[1-[4-(piperidine-1-sulfonyl)-phenyl]-eth-(E)-ylidene]-hydrazono}-thiazolidin-4-one 
• 202660-58-0 2-Benzenesulfonyl-1-[4-(piperidine-1-sulfonyl)-phenyl]-ethanone 
• 215783-65-6 (5-Imino-4-phenyl-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-[4-(piperidine-1-sulfonyl)-phenyl]-methanone 
• 215783-75-8 (5-Imino-4-phenyl-4,5-dihydro-[1,3,4]selenadiazol-2-yl)-[4-(piperidine-1-sulfonyl)-phenyl]-methanone 
• 215783-68-9 (5-Imino-4-p-tolyl-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-[4-(piperidine-1-sulfonyl)-phenyl]-methanone 
• 215783-77-0 (5-Imino-4-p-tolyl-4,5-dihydro-[1,3,4]selenadiazol-2-yl)-[4-(piperidine-1-sulfonyl)-phenyl]-methanone 

Relevant articles and documents

Synthesis and structure-activity relationship of aminopyrimidine IKK2 inhibitors

The synthesis and structure-activity relationship of a novel series of aminopyrimidines are exemplified. Results of key compounds from within this series in the E-selectin reporter cell assay are also reported.

Novel antibacterial amide compounds and process means for producing the same

Novel organic amide compounds which are N-[6-[(aminosulfonyl)phenyl]-1,2-dihydro-2-oxonicotinyl]penicillin and cephalosporin type compounds having broad spectrum antibacterial utility are provided by (a) reacting the free amino acid of the appropriate penicillin or cephalosporin or the acid salt or silylated derivative or complex thereof with a reactive derivative of the corresponing N-6-[(aminosulfonyl)phenyl]-1,2-dihydro-2-oxonicotinic acid or (b) reacting the free amino acid 6-aminopenicillanic acid, 7-aminocephalosporanic acid, 7-amino-3-methylceph-3-em-4-carboxylic acid or a related compound or the acid salt or silylated derivative thereof with a reactive derivative of the corresponding D-N-[6-[(aminosulfonyl)phenyl]-1,2-dihydro-2-oxonicotinyl]-2-substituted glycine. Pharmaceutical compositions containing said compounds and methods for treating infections using said compositions are also disclosed.