58737-22-7 Usage
Description
P-AMINOPHENYL-1-THIO-BETA-D-GLUCOPYRANOS IDE, also known as 4-Aminophenyl 1-Thio-β-D-glucopyranoside, is a glycoside derivative of 4-Amino-benzenethiol (A591510). It is a chemical compound that plays a significant role in the synthesis of various pharmaceutical agents due to its unique structure and properties.
Uses
Used in Pharmaceutical Industry:
P-AMINOPHENYL-1-THIO-BETA-D-GLUCOPYRANOS IDE is used as a key intermediate compound for the preparation of CCR5 antagonists, which are anti-HIV-1 agents. Its unique structure allows it to be a crucial component in the development of these life-saving medications, contributing to the fight against HIV-1.
Used in Chemical Synthesis:
P-AMINOPHENYL-1-THIO-BETA-D-GLUCOPYRANOS IDE is also used as a starting material to synthesize functionalized Coumarins (C755380), which are known as acetylcholinesterase inhibitors. These inhibitors play a vital role in the treatment of various neurological disorders, such as Alzheimer's disease, by regulating the levels of acetylcholine in the brain.
Check Digit Verification of cas no
The CAS Registry Mumber 58737-22-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,7,3 and 7 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 58737-22:
(7*5)+(6*8)+(5*7)+(4*3)+(3*7)+(2*2)+(1*2)=157
157 % 10 = 7
So 58737-22-7 is a valid CAS Registry Number.
58737-22-7Relevant articles and documents
Enzymatic Synthesis of a Series of Thioglycosides: Analogs of Arbutin with Efficient Antipigmentation Properties
Daniellou, Richard,Didak, Blanka,Guillotin, Laure,Lafite, Pierre,Landemarre, Ludovic,Lemiègre, Lo?c,Peyrot, Cédric
, p. 3812 - 3818 (2021/08/24)
Arbutin, a natural glycoside, is well known as a commercial tyrosinase inhibitor, and thus, to prevent pigmentary disorders of skin. In fact, tyrosinase is involved in the biosynthesis of melanin, the skin main pigment. However, arbutin is subject to hydr
Substituted phenyl-1-thio(poly-O-sulfo)-α(or β)-D-glucopyranosides
-
, (2008/06/13)
Cation salts of substituted phenyl-1-thio(poly-O-sulfo)-α(or β)-D-glucopyranoside, useful as modulators of the complement system, the intermediates thereof and the process of making such intermediates and end products.
